Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GLRA2 [plasma membrane]
Stable Identifier
R-HSA-975383
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Glycine receptor subunit alpha-2, GLRA2_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
GLRA:GLRB:Gly transports extracellular Cl- to cytosol (Homo sapiens)
GLRA:GLRB:Gly [plasma membrane] (Homo sapiens)
GLRA1,2,3 [plasma membrane] (Homo sapiens)
GLRA2 [plasma membrane] (Homo sapiens)
NBEA binds GLRB (Homo sapiens)
GLRA:GLRB heteropentamer [plasma membrane] (Homo sapiens)
GLRA1,2,3 [plasma membrane] (Homo sapiens)
GLRA2 [plasma membrane] (Homo sapiens)
GLRA:GLRB heteropentamer:NBEA [plasma membrane] (Homo sapiens)
GLRA:GLRB heteropentamer [plasma membrane] (Homo sapiens)
GLRA1,2,3 [plasma membrane] (Homo sapiens)
GLRA2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P23416 GLRA2
Gene Names
GLRA2
Chain
signal peptide:1-27, chain:28-452
Reference Genes
BioGPS Gene:2742 GLRA2
COSMIC (genes):GLRA2 GLRA2
CTD Gene:2742 GLRA2
dbSNP Gene:2742 GLRA2
ENSEMBL:ENSG00000101958 GLRA2
HGNC:4327 GLRA2
KEGG:hsa:2742 GLRA2
Monarch:2742 GLRA2
NCBI Gene:2742 GLRA2
OMIM:305990 GLRA2
UCSC:P23416 GLRA2
Reference Transcript
RefSeq:NM_001118886.1 GLRA2
RefSeq:NM_001171942.1 GLRA2
RefSeq:NM_002063.3 GLRA2
RefSeq:XM_017029428.1 GLRA2
RefSeq:XM_017029429.1 GLRA2
RefSeq:XM_017029427.1 GLRA2
RefSeq:NM_001118885.1 GLRA2
Other Identifiers
11732207_a_at
11752526_a_at
17101660
207462_PM_at
207462_at
2742
34554_at
3969658
3969659
3969660
3969661
3969662
3969663
3969664
3969666
3969667
3969674
3969675
3969677
3969683
3969684
3969685
3969686
3969697
3969698
3969705
3969706
66488_at
8166127
A_14_P101232
A_23_P411903
A_33_P3337049
GE59765
GO:0004888
GO:0005215
GO:0005216
GO:0005230
GO:0005254
GO:0005886
GO:0006811
GO:0006821
GO:0007218
GO:0016020
GO:0016594
GO:0016934
GO:0022824
GO:0022852
GO:0030594
GO:0034220
GO:0034707
GO:0042995
GO:0043005
GO:0043226
GO:0043231
GO:0045202
GO:0045211
GO:0046872
GO:0050804
GO:0055085
GO:0060078
GO:0060079
GO:0060089
GO:0071230
GO:0071294
GO:0071361
GO:0098690
GO:0098982
GO:0099634
GO:1902476
GO:1902495
GO:1904315
HMNXSV003011215
ILMN_1788786
PH_hs_0000350
TC0X000065.hg
X52008_at
g4504020_3p_at
Participates
as a member of
GLRA1,2,3 [plasma membrane] (Homo sapiens)
Inferred To
avr-14 [plasma membrane]
(Caenorhabditis elegans)
GLRA2 [plasma membrane]
(Bos taurus)
GLRA2 [plasma membrane]
(Canis familiaris)
GLRA2 [plasma membrane]
(Danio rerio)
GLRA2 [plasma membrane]
(Drosophila melanogaster)
GLRA2 [plasma membrane]
(Gallus gallus)
GLRA2 [plasma membrane]
(Mus musculus)
GLRA2 [plasma membrane]
(Rattus norvegicus)
GLRA2 [plasma membrane]
(Sus scrofa)
GLRA2 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001165413.1
,
XP_016884918.1
,
NP_002054.1
,
XP_016884916.1
,
NP_001112358.1
,
NP_001112357.1
,
XP_016884917.1
ZINC - World Drugs
GLRA2_HUMAN
Guide to Pharmacology - Targets
424
ENSEMBL
ENST00000218075
,
ENSP00000218075
,
ENST00000355020
,
ENSP00000347123
OpenTargets
ENSG00000101958
ZINC - Substances
GLRA2_HUMAN
ZINC - Biogenic
GLRA2_HUMAN
ZINC target
P23416
PRO
P23416
GlyGen
P23416
PDB
7KUY
,
7L31
,
5BKG
,
5BKF
HPA
ENSG00000101958-GLRA2
Pharos - Targets
P23416
ZINC - Predictions - Purchasable
GLRA2_HUMAN
HMDB Protein
HMDBP08217
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text