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GABRA5 [plasma membrane]
Stable Identifier
R-HSA-975376
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Gamma-aminobutyric acid receptor subunit alpha-5, GBRA5_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
GABA receptor activation (Homo sapiens)
GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Homo sapiens)
GABR heteropentamers:GABA [plasma membrane] (Homo sapiens)
GABR heteropentamers [plasma membrane] (Homo sapiens)
2GABRA:2GABRB:GABRG [plasma membrane] (Homo sapiens)
GABRAs [plasma membrane] (Homo sapiens)
GABRA5 [plasma membrane] (Homo sapiens)
2GABRA:GABRB:GABRG:GABRQ [plasma membrane] (Homo sapiens)
GABRAs [plasma membrane] (Homo sapiens)
GABRA5 [plasma membrane] (Homo sapiens)
NPTN binds GABA A receptors (Homo sapiens)
GABR heteropentamers:GABA [plasma membrane] (Homo sapiens)
GABR heteropentamers [plasma membrane] (Homo sapiens)
2GABRA:2GABRB:GABRG [plasma membrane] (Homo sapiens)
GABRAs [plasma membrane] (Homo sapiens)
GABRA5 [plasma membrane] (Homo sapiens)
2GABRA:GABRB:GABRG:GABRQ [plasma membrane] (Homo sapiens)
GABRAs [plasma membrane] (Homo sapiens)
GABRA5 [plasma membrane] (Homo sapiens)
GABR heteropentamers:GABA:NPTN [plasma membrane] (Homo sapiens)
GABR heteropentamers:GABA [plasma membrane] (Homo sapiens)
GABR heteropentamers [plasma membrane] (Homo sapiens)
2GABRA:2GABRB:GABRG [plasma membrane] (Homo sapiens)
GABRAs [plasma membrane] (Homo sapiens)
GABRA5 [plasma membrane] (Homo sapiens)
2GABRA:GABRB:GABRG:GABRQ [plasma membrane] (Homo sapiens)
GABRAs [plasma membrane] (Homo sapiens)
GABRA5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P31644 GABRA5
Gene Names
GABRA5
Chain
signal peptide:1-31, chain:32-462
Reference Genes
BioGPS Gene:2558 GABRA5
COSMIC (genes):GABRA5 GABRA5
CTD Gene:2558 GABRA5
dbSNP Gene:2558 GABRA5
ENSEMBL:ENSG00000186297 GABRA5
ENSEMBL_homo_sapiens_GENE:ENSG00000186297.12 GABRA5
HGNC:4079 GABRA5
KEGG Gene (Homo sapiens):2558 GABRA5
Monarch:2558 GABRA5
NCBI Gene:2558 GABRA5
OMIM:137142 GABRA5
UCSC:P31644 GABRA5
Reference Transcript
RefSeq:NM_000810.3 GABRA5
RefSeq:XM_005268258.2 GABRA5
RefSeq:XM_006720459.2 GABRA5
RefSeq:NM_001165037.1 GABRA5
Other Identifiers
11736353_at
16798479
206456_PM_at
206456_at
215531_PM_s_at
215531_s_at
217280_3p_x_at
217280_PM_x_at
217280_x_at
2558
3585238
3585239
3585242
3585243
3585244
3585251
3585252
3585255
3585258
3585260
3585265
3585266
3585267
39321_at
4039132
4039133
4039134
4039137
4039138
4039142
4039144
4039145
4039529
7982102
A_14_P118020
A_23_P436618
GE58234
GO:0001662
GO:0004888
GO:0004890
GO:0005215
GO:0005216
GO:0005230
GO:0005237
GO:0005254
GO:0005634
GO:0005654
GO:0005829
GO:0005886
GO:0006811
GO:0006821
GO:0007165
GO:0007214
GO:0007268
GO:0008306
GO:0008503
GO:0016020
GO:0022851
GO:0023052
GO:0030154
GO:0030425
GO:0032590
GO:0032809
GO:0034220
GO:0034707
GO:0038023
GO:0042734
GO:0043005
GO:0043226
GO:0043235
GO:0044297
GO:0045202
GO:0045211
GO:0048666
GO:0048856
GO:0050811
GO:0050877
GO:0051932
GO:0055085
GO:0060078
GO:0060089
GO:0060119
GO:0060384
GO:0090102
GO:0098794
GO:0098982
GO:0099505
GO:0099507
GO:0099634
GO:1902476
GO:1902711
GO:1904315
HMNXSV003043760
Hs.24969.1.S1_3p_a_at
Hs.24969.2.S1_3p_a_at
Hs.24969.2.S1_3p_x_at
ILMN_1707571
ILMN_2215730
L08485_at
PH_hs_0002192
PH_hs_0037597
TC15000124.hg
g6031207_3p_at
p33779
Participates
as a member of
GABRAs [plasma membrane] (Homo sapiens)
Inferred To
gabra5 [plasma membrane]
(Xenopus tropicalis)
Lcch-14A [plasma membrane]
(Drosophila melanogaster)
Gabra5 [plasma membrane]
(Mus musculus)
Gabra5 [plasma membrane]
(Rattus norvegicus)
Grd [plasma membrane]
(Drosophila melanogaster)
Homologues of GABRA5 [plasma membrane]
(Caenorhabditis elegans)
Homologues of GABRA5 [plasma membrane]
(Drosophila melanogaster)
lgc-36 [plasma membrane]
(Caenorhabditis elegans)
GABRA5 [plasma membrane]
(Bos taurus)
GABRA5 [plasma membrane]
(Canis familiaris)
GABRA5 [plasma membrane]
(Gallus gallus)
GABRA5 [plasma membrane]
(Sus scrofa)
lgc-37 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
XP_006720522.1
,
NP_001158509.1
,
XP_005268315.1
,
NP_000801.1
ZINC - World Drugs
GBRA5_HUMAN
Guide to Pharmacology - Targets
408
OpenTargets
ENSG00000186297
ZINC - FDA approved
GBRA5_HUMAN
ZINC - Substances
GBRA5_HUMAN
ZINC target
P31644
PRO
P31644
PDB
6A96
,
5OJM
,
5O8F
ZINC - Investigational
GBRA5_HUMAN
HPA
ENSG00000186297-GABRA5
GeneCards
P31644
Ensembl
ENST00000400081
,
ENST00000355395
,
ENSP00000347557
,
ENSG00000186297
,
ENSP00000382953
,
ENSP00000335592
,
ENST00000335625
Pharos - Targets
P31644
Orphanet
27143
ZINC - Predictions - Purchasable
GBRA5_HUMAN
HMDB Protein
HMDBP08202
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