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HTR3A [plasma membrane]
Stable Identifier
R-HSA-975301
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
5-hydroxytryptamine receptor 3A, 5HT3A_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Homo sapiens)
HTR3 pentamers:5HT [plasma membrane] (Homo sapiens)
HTR3 pentamers [plasma membrane] (Homo sapiens)
2xHTR3A:3xHTR3B [plasma membrane] (Homo sapiens)
HTR3A [plasma membrane] (Homo sapiens)
2xHTR3A:3xHTR3C [plasma membrane] (Homo sapiens)
HTR3A [plasma membrane] (Homo sapiens)
2xHTR3A:3xHTR3D [plasma membrane] (Homo sapiens)
HTR3A [plasma membrane] (Homo sapiens)
2xHTR3A:3xHTR3E [plasma membrane] (Homo sapiens)
HTR3A [plasma membrane] (Homo sapiens)
HTR3A antagonists bind HTR3A pentamer (Homo sapiens)
HTR3A pentamer [plasma membrane] (Homo sapiens)
HTR3A [plasma membrane] (Homo sapiens)
HTR3A pentamer:HTR3A antagonists [plasma membrane] (Homo sapiens)
HTR3A pentamer:5HT [plasma membrane] (Homo sapiens)
HTR3A [plasma membrane] (Homo sapiens)
HTR3A pentamer binds 5HT (Homo sapiens)
HTR3A pentamer [plasma membrane] (Homo sapiens)
HTR3A [plasma membrane] (Homo sapiens)
HTR3A pentamer:5HT [plasma membrane] (Homo sapiens)
HTR3A [plasma membrane] (Homo sapiens)
HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Homo sapiens)
HTR3A pentamer:5HT [plasma membrane] (Homo sapiens)
HTR3A [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P46098 HTR3A
Gene Names
HTR3A, 5HT3R, HTR3
Chain
signal peptide:1-23, chain:24-478
Reference Genes
BioGPS Gene:3359 HTR3A
COSMIC (genes):HTR3A HTR3A
CTD Gene:3359 HTR3A
dbSNP Gene:3359 HTR3A
ENSEMBL:ENSG00000166736 HTR3A
HGNC:5297 HTR3A
KEGG:hsa:3359 HTR3A
Monarch:3359 HTR3A
NCBI Gene:3359 HTR3A
OMIM:182139 HTR3A
UCSC:P46098 HTR3A
Reference Transcript
RefSeq:NM_213621.3 HTR3A
RefSeq:NM_000869.5 HTR3A
RefSeq:NM_001161772.2 HTR3A
Other Identifiers
11726229_a_at
11739827_a_at
16731422
216615_PM_s_at
216615_s_at
217002_PM_s_at
217002_s_at
3349689
3349690
3349691
3349692
3349693
3349694
3349695
3349697
3349698
3349699
3349700
3349701
3349702
3349703
3359
740_at
741_g_at
7943969
A_23_P98399
A_24_P150068
D49394_at
GE55159
GO:0004888
GO:0005215
GO:0005216
GO:0005230
GO:0005231
GO:0005515
GO:0005886
GO:0006811
GO:0007210
GO:0015276
GO:0016020
GO:0022848
GO:0022850
GO:0032154
GO:0034220
GO:0042802
GO:0043005
GO:0045202
GO:0045211
GO:0051378
GO:0055085
GO:0060078
GO:0060079
GO:0060089
GO:0098662
GO:0099505
GO:0099507
GO:0140227
GO:1902495
GO:1904315
GO:1904602
HMNXSV003003169
Hs.2142.1.S1_3p_a_at
Hs.2142.2.S1_3p_a_at
ILMN_1662070
ILMN_1681492
ILMN_2371079
PH_hs_0019589
TC11001025.hg
Participates
as a component of
HTR3A pentamer [plasma membrane] (Homo sapiens)
HTR3A pentamer:5HT [plasma membrane] (Homo sapiens)
2xHTR3A:3xHTR3D [plasma membrane] (Homo sapiens)
2xHTR3A:3xHTR3E [plasma membrane] (Homo sapiens)
2xHTR3A:3xHTR3B [plasma membrane] (Homo sapiens)
2xHTR3A:3xHTR3C [plasma membrane] (Homo sapiens)
Inferred To
Homologues of HTR3A [plasma membrane]
(Caenorhabditis elegans)
lgc-7 [plasma membrane]
(Caenorhabditis elegans)
lgc-9 [plasma membrane]
(Caenorhabditis elegans)
lgc-4 [plasma membrane]
(Caenorhabditis elegans)
lgc-12 [plasma membrane]
(Caenorhabditis elegans)
lgc-31 [plasma membrane]
(Caenorhabditis elegans)
lgc-6 [plasma membrane]
(Caenorhabditis elegans)
acr-20 [plasma membrane]
(Caenorhabditis elegans)
lgc-11 [plasma membrane]
(Caenorhabditis elegans)
lgc-8 [plasma membrane]
(Caenorhabditis elegans)
deg-3 [plasma membrane]
(Caenorhabditis elegans)
acr-23 [plasma membrane]
(Caenorhabditis elegans)
acr-5 [plasma membrane]
(Caenorhabditis elegans)
HTR3A [plasma membrane]
(Bos taurus)
HTR3A [plasma membrane]
(Canis familiaris)
HTR3A [plasma membrane]
(Sus scrofa)
lgc-10 [plasma membrane]
(Caenorhabditis elegans)
acr-24 [plasma membrane]
(Caenorhabditis elegans)
acr-21 [plasma membrane]
(Caenorhabditis elegans)
lgc-5 [plasma membrane]
(Caenorhabditis elegans)
Htr3a [plasma membrane]
(Mus musculus)
Htr3a [plasma membrane]
(Rattus norvegicus)
des-2 [plasma membrane]
(Caenorhabditis elegans)
lgc-30 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001155244.1
,
NP_000860.2
,
NP_998786.2
ZINC - World Drugs
5HT3A_HUMAN
Guide to Pharmacology - Targets
373
ENSEMBL
ENSP00000364648
,
ENSP00000424189
,
ENSP00000424776
,
ENST00000506841
,
ENSP00000299961
,
ENST00000375498
,
ENSP00000347754
,
ENST00000299961
,
ENST00000504030
,
ENST00000355556
OpenTargets
ENSG00000166736
ZINC - FDA approved
5HT3A_HUMAN
ZINC - Substances
5HT3A_HUMAN
ZINC - Biogenic
5HT3A_HUMAN
ZINC target
P46098
PRO
P46098
GlyGen
P46098
PDB
8BLA
,
8BLB
,
8BL8
,
8AXD
ZINC - Investigational
5HT3A_HUMAN
ZINC - Metabolites
5HT3A_HUMAN
HPA
ENSG00000166736-HTR3A
Pharos - Targets
P46098
ZINC - Predictions - Purchasable
5HT3A_HUMAN
HMDB Protein
HMDBP02917
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