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GABRG3 [plasma membrane]
Stable Identifier
R-HSA-975261
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Gamma-aminobutyric acid receptor subunit gamma-3, GBRG3_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
GABA receptor activation (Homo sapiens)
GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Homo sapiens)
GABR heteropentamers:GABA [plasma membrane] (Homo sapiens)
GABR heteropentamers [plasma membrane] (Homo sapiens)
2GABRA:2GABRB:GABRG [plasma membrane] (Homo sapiens)
GABRGs [plasma membrane] (Homo sapiens)
GABRG3 [plasma membrane] (Homo sapiens)
2GABRA:GABRB:GABRG:GABRQ [plasma membrane] (Homo sapiens)
GABRGs [plasma membrane] (Homo sapiens)
GABRG3 [plasma membrane] (Homo sapiens)
NPTN binds GABA A receptors (Homo sapiens)
GABR heteropentamers:GABA [plasma membrane] (Homo sapiens)
GABR heteropentamers [plasma membrane] (Homo sapiens)
2GABRA:2GABRB:GABRG [plasma membrane] (Homo sapiens)
GABRGs [plasma membrane] (Homo sapiens)
GABRG3 [plasma membrane] (Homo sapiens)
2GABRA:GABRB:GABRG:GABRQ [plasma membrane] (Homo sapiens)
GABRGs [plasma membrane] (Homo sapiens)
GABRG3 [plasma membrane] (Homo sapiens)
GABR heteropentamers:GABA:NPTN [plasma membrane] (Homo sapiens)
GABR heteropentamers:GABA [plasma membrane] (Homo sapiens)
GABR heteropentamers [plasma membrane] (Homo sapiens)
2GABRA:2GABRB:GABRG [plasma membrane] (Homo sapiens)
GABRGs [plasma membrane] (Homo sapiens)
GABRG3 [plasma membrane] (Homo sapiens)
2GABRA:GABRB:GABRG:GABRQ [plasma membrane] (Homo sapiens)
GABRGs [plasma membrane] (Homo sapiens)
GABRG3 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ERBB4 (Homo sapiens)
NRG2-activated ERBB4 binds GABA receptors through GABRA1 (Homo sapiens)
GABRA1 heteropentamers:GABA [plasma membrane] (Homo sapiens)
GABRA1 heteropentamers [plasma membrane] (Homo sapiens)
2GABRA1:2GABRB:GABRG [plasma membrane] (Homo sapiens)
GABRGs [plasma membrane] (Homo sapiens)
GABRG3 [plasma membrane] (Homo sapiens)
2GABRA1:GABRB:GABRG:GABRQ [plasma membrane] (Homo sapiens)
GABRGs [plasma membrane] (Homo sapiens)
GABRG3 [plasma membrane] (Homo sapiens)
NRG2:p-ERBB4 homodimers:GABRA1 heteropentamers:GABA [plasma membrane] (Homo sapiens)
GABRA1 heteropentamers:GABA [plasma membrane] (Homo sapiens)
GABRA1 heteropentamers [plasma membrane] (Homo sapiens)
2GABRA1:2GABRB:GABRG [plasma membrane] (Homo sapiens)
GABRGs [plasma membrane] (Homo sapiens)
GABRG3 [plasma membrane] (Homo sapiens)
2GABRA1:GABRB:GABRG:GABRQ [plasma membrane] (Homo sapiens)
GABRGs [plasma membrane] (Homo sapiens)
GABRG3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99928 GABRG3
Gene Names
GABRG3
Chain
signal peptide:1-17, chain:18-467
Reference Genes
BioGPS Gene:2567 GABRG3
COSMIC (genes):GABRG3 GABRG3
CTD Gene:2567 GABRG3
dbSNP Gene:2567 GABRG3
ENSEMBL:ENSG00000182256 GABRG3
ENSEMBL_homo_sapiens_GENE:ENSG00000182256.13 GABRG3
HGNC:4088 GABRG3
KEGG Gene (Homo sapiens):2567 GABRG3
Monarch:2567 GABRG3
NCBI Gene:2567 GABRG3
OMIM:600233 GABRG3
UCSC:Q99928 GABRG3
Reference Transcript
RefSeq:NM_001270873.1 GABRG3
RefSeq:NM_033223.4 GABRG3
Other Identifiers
11742122_at
1555517_PM_at
1555517_at
16798496
216895_PM_at
216895_at
2567
31567_at
3585273
3585274
3585275
3585281
3585320
3585335
3585336
3585337
3585341
3585342
3585343
3585344
3585345
3585346
3585347
3585363
3585365
3585367
3585369
3585371
3585372
3585373
3585375
3585377
3585379
7982117
A_14_P106800
A_14_P128642
A_23_P332268
A_23_P43864
A_32_P74831
A_33_P3210805
GE58825
GE871202
GO:0004888
GO:0004890
GO:0005215
GO:0005216
GO:0005230
GO:0005237
GO:0005254
GO:0005634
GO:0005730
GO:0005856
GO:0005886
GO:0006811
GO:0006821
GO:0007214
GO:0008503
GO:0009410
GO:0015630
GO:0016020
GO:0022851
GO:0023052
GO:0032590
GO:0034220
GO:0034707
GO:0043005
GO:0043226
GO:0045202
GO:0045211
GO:0051932
GO:0055085
GO:0060078
GO:0060089
GO:0097060
GO:0098794
GO:0098982
GO:1902476
GO:1902711
GO:1904315
HMNXSV003018756
Hs.104133.0.S1_3p_at
Hs2Affx.1.344.S1_3p_at
ILMN_1725808
PH_hs_0005779
PH_hs_0013438
TC15000125.hg
Participates
as a member of
GABRGs [plasma membrane] (Homo sapiens)
Inferred To
gabrg3 [plasma membrane]
(Xenopus tropicalis)
Lcch-14A [plasma membrane]
(Drosophila melanogaster)
Grd [plasma membrane]
(Drosophila melanogaster)
Gabrg3 [plasma membrane]
(Mus musculus)
Gabrg3 [plasma membrane]
(Rattus norvegicus)
lgc-36 [plasma membrane]
(Caenorhabditis elegans)
Homologues of GABRG3 [plasma membrane]
(Caenorhabditis elegans)
Homologues of GABRG3 [plasma membrane]
(Drosophila melanogaster)
lgc-37 [plasma membrane]
(Caenorhabditis elegans)
GABRG3 [plasma membrane]
(Bos taurus)
GABRG3 [plasma membrane]
(Canis familiaris)
GABRG3 [plasma membrane]
(Gallus gallus)
GABRG3 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_150092.2
,
NP_001257802.1
Guide to Pharmacology - Targets
415
OpenTargets
ENSG00000182256
HPA
ENSG00000182256-GABRG3
GeneCards
Q99928
Ensembl
ENST00000555083
,
ENST00000615808
,
ENSP00000479113
,
ENSP00000452244
,
ENSG00000182256
PRO
Q99928
Pharos - Targets
Q99928
Orphanet
27144
HMDB Protein
HMDBP08210
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