K63-linked poly-Ub-IRF7:TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9. [endosome membrane]

Stable Identifier
R-HSA-975174
Type
Complex
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1, Influenza A virus, Human SARS coronavirus, Severe acute respiratory syndrome coronavirus 2
Compartment
endosome membrane
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
15361868 Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

Kawai, T, Takeuchi, O, Inoue, J, Matsuda, M, Terai, K, Ishii, KJ, Sato, S, Yamamoto, M, Akira, S, Uematsu, S, Coban, C, Hemmi, H

Nat Immunol 2004
Participants
components
Participates
as an output of
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