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TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane]
Stable Identifier
R-HSA-975121
Type
Complex
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Homo sapiens)
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Homo sapiens)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane] (Homo sapiens)
Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Homo sapiens)
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Homo sapiens)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane] (Homo sapiens)
Participants
components
CHUK:IKBKB:IKBKG [cytosol]
(Homo sapiens)
K63-linked poly-Ub-p-3S,3T-IRAK1:TRAF6 [endosome membrane]
(Homo sapiens)
Participates
as an output of
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Homo sapiens)
Inferred To
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane]
(Bos taurus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane]
(Canis familiaris)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane]
(Drosophila melanogaster)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane]
(Mus musculus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane]
(Rattus norvegicus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane]
(Sus scrofa)
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