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ORC(1-5):origin of replication [nucleoplasm]
Stable Identifier
R-HSA-9749104
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Replication (Homo sapiens)
DNA Replication Pre-Initiation (Homo sapiens)
Assembly of the pre-replicative complex (Homo sapiens)
ATP-dependent release of CDT1 from the OCCM complex (Homo sapiens)
ORC(1-6):CDC6:origin of replication:CDT1:MCM2-7 [nucleoplasm] (Homo sapiens)
ORC(1-6):CDC6:origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):CDC6:origin of replication:MCM2-7 [nucleoplasm] (Homo sapiens)
ORC(1-6):CDC6:origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
Assembly of the ORC complex at the origin of replication (Homo sapiens)
Formation of ORC(1-5) complex (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
Formation of ORC(1-6) complex (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
CDC6 association with the ORC:origin complex (Homo sapiens)
CDC6 association with ORC(1-6) at replication origins (Homo sapiens)
ORC(1-6):CDC6:origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
CDT1-mediated formation of MCM2-7 double hexamer at the replication origin (Homo sapiens)
ORC(1-6):CDC6:origin of replication:MCM2-7 [nucleoplasm] (Homo sapiens)
ORC(1-6):CDC6:origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):CDC6:origin or replication:MCM2-7 double hexamer [nucleoplasm] (Homo sapiens)
ORC(1-6):CDC6:origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
CDT1-mediated loading of MCM2-7 to replication origins (Homo sapiens)
ORC(1-6):CDC6:origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):CDC6:origin of replication:CDT1:MCM2-7 [nucleoplasm] (Homo sapiens)
ORC(1-6):CDC6:origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-6):origin of replication [nucleoplasm] (Homo sapiens)
ORC(1-5):origin of replication [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
16762929
Genetic analysis of human Orc2 reveals specific domains that are required in vivo for assembly and nuclear localization of the origin recognition complex
Radichev, I
,
Zhao, Y
,
Vassilev, A
,
Kwon, SW
,
DePamphilis, ML
J Biol Chem
2006
Participants
components
ORC(1-5) [nucleoplasm]
(Homo sapiens)
origin of replication [nucleoplasm]
(Homo sapiens)
Participates
as an input of
Formation of ORC(1-6) complex (Homo sapiens)
as an output of
Formation of ORC(1-5) complex (Homo sapiens)
as a component of
ORC(1-6):origin of replication [nucleoplasm] (Homo sapiens)
Inferred To
ORC(1-5):origin of replication [nucleoplasm]
(Bos taurus)
ORC(1-5):origin of replication [nucleoplasm]
(Caenorhabditis elegans)
ORC(1-5):origin of replication [nucleoplasm]
(Canis familiaris)
ORC(1-5):origin of replication [nucleoplasm]
(Dictyostelium discoideum)
ORC(1-5):origin of replication [nucleoplasm]
(Drosophila melanogaster)
ORC(1-5):origin of replication [nucleoplasm]
(Gallus gallus)
ORC(1-5):origin of replication [nucleoplasm]
(Mus musculus)
ORC(1-5):origin of replication [nucleoplasm]
(Rattus norvegicus)
ORC(1-5):origin of replication [nucleoplasm]
(Saccharomyces cerevisiae)
ORC(1-5):origin of replication [nucleoplasm]
(Schizosaccharomyces pombe)
ORC(1-5):origin of replication [nucleoplasm]
(Sus scrofa)
ORC(1-5):origin of replication [nucleoplasm]
(Xenopus tropicalis)
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