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p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2:MYC gene [nucleoplasm]
Stable Identifier
R-HSA-9736985
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Homo sapiens)
MYC trancscription is negatively regulated by SMAD2/3:SMAD4:RBL1:E2F4/5:DP1/2 complex (Homo sapiens)
p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2:MYC gene [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2 binds MYC gene promoter (Homo sapiens)
p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2:MYC gene [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by TGF-beta Receptor Complex (Homo sapiens)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Homo sapiens)
MYC trancscription is negatively regulated by SMAD2/3:SMAD4:RBL1:E2F4/5:DP1/2 complex (Homo sapiens)
p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2:MYC gene [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2 binds MYC gene promoter (Homo sapiens)
p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2:MYC gene [nucleoplasm] (Homo sapiens)
Participants
components
MYC gene [nucleoplasm]
(Homo sapiens)
p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2 [nucleoplasm]
(Homo sapiens)
Participates
as an output of
p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2 binds MYC gene promoter (Homo sapiens)
This entity regulates
Negatively
MYC trancscription is negatively regulated by SMAD2/3:SMAD4:RBL1:E2F4/5:DP1/2 complex
(Homo sapiens)
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