WWTR1:p-2S-SMAD2,3:SMAD4 binds SMAD7 gene promoter

Stable Identifier
R-HSA-9736970
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Chromatin immunoprecipitation (ChIP) confirmed binding of both WWTR1 and SMAD2,3:SMAD4 complex to the promoter of SMAD7 gene in response to TGF-beta stimulation (Varelas et al. 2008).

Literature References
PubMed ID Title Journal Year
18568018 TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

Varelas, X, Sakuma, R, Samavarchi-Tehrani, P, Peerani, R, Rao, BM, Dembowy, J, Yaffe, MB, Zandstra, PW, Wrana, JL

Nat Cell Biol 2008
Participants
Participates
Authored
Reviewed
Created
Cite Us!