WWTR1:p-2S-SMAD2,3:SMAD4 binds SMAD7 gene promoter

Stable Identifier
R-HSA-9736970
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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WWTR1:p-2S-SMAD2,3:SMAD4 binds SMAD7 gene promoter
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Chromatin immunoprecipitation (ChIP) confirmed binding of both WWTR1 and SMAD2,3:SMAD4 complex to the promoter of SMAD7 gene in response to TGF-beta stimulation (Varelas et al. 2008).
Literature References
PubMed ID Title Journal Year
18568018 TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

Wrana, JL, Peerani, R, Rao, BM, Samavarchi-Tehrani, P, Sakuma, R, Zandstra, PW, Varelas, X, Yaffe, MB, Dembowy, J

Nat Cell Biol 2008
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Authored
Orlic-Milacic, M  (2012-04-05)
Reviewed
Huang, T  (2012-05-14)
Contreras, O  (2022-05-02)
Created
Orlic-Milacic, M  (2021-07-15)
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