GATA4 and LEF1:CTNNB1 bind the ISL1 gene

Stable Identifier
R-HSA-9735179
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
GATA4 and LEF1:CTNNB1 bind the ISL1 gene
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
GATA4 and LEF1:CTNNB1 (beta-catenin) bind the promoter of the ISL1 gene in the second heart field (SHF) during cardiogenesis (inferred from mouse homologs). TBX1 also positively regulates transcription of ISL1 and based on nucleotide sequence is believed to bind the ISL1 promoter (inferred from mouse homologs).
Participants
Input
Output
Participates
as an event of
Inferred From
Gata4 and Lef1:Ctnnb1 bind the Isl1 gene (Mus musculus)
Authored
May, B  (2021-06-22)
Created
May, B  (2021-06-23)
Cite Us!