ORC6 translocates to the nucleus

Stable Identifier
R-HSA-9734713
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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Phosphorylation at threonine residue T195 facilitates translocation of ORC6 to the nucleus (Ghosh et al. 2011). In the nucleus, ORC6 is thought to dissociate from the importin complex.

Literature References
PubMed ID Title Journal Year
21555516 Assembly of the human origin recognition complex occurs through independent nuclear localization of its components

Ghosh, S, Vassilev, AP, Zhang, J, Zhao, Y, DePamphilis, ML

J Biol Chem 2011
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