Expression of TBX5 in cardiogenesis

Stable Identifier
R-HSA-9734343
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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Expression of TBX5 in cardiogenesis
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The TBX5 gene is transcribed to yield mRNA and the mRNA is translated to yield TBX5 protein. Expression of TBX5 is enhanced by NKX2-5 in the first heart field (FHF) during cardiogenesis (Sun et al. 2004).
Literature References
PubMed ID Title Journal Year
15095414 TBX5, a gene mutated in Holt-Oram syndrome, is regulated through a GC box and T-box binding elements (TBEs)

Price, C, Lewis, LE, Nguyen, Q, Huang, X, Huang, T, Sun, G

J Cell Biochem 2004
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
NKX2-5:TBX5 gene [nucleoplasm] (Homo sapiens)
Inferred From
Expression of Tbx5 in cardiogenesis (Mus musculus)
Authored
May, B  (2021-06-10)
Created
May, B  (2021-06-17)
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