NKX2-5 binds the TBX5 gene

Stable Identifier
R-HSA-9734337
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
NKX2-5 binds the TBX5 gene
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
NKX2-5 binds a site in the promoter of the TBX5 gene about 45 nucleotides upstream of the transcription start site (Sun et al. 2004, and inferred from mouse homologs).
Literature References
PubMed ID Title Journal Year
15095414 TBX5, a gene mutated in Holt-Oram syndrome, is regulated through a GC box and T-box binding elements (TBEs)

Sun, G, Lewis, LE, Huang, X, Nguyen, Q, Price, C, Huang, T

J Cell Biochem 2004
Participants
Input
Output
Participates
as an event of
Inferred From
Nkx2-5 binds the Tbx5 gene (Mus musculus)
Authored
May, B  (2021-06-10)
Created
May, B  (2021-06-17)
Cite Us!