Bile salts bind FABP6

Stable Identifier
R-HSA-9733973
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cytosolic ileal bile acid binding protein (IBABP, FABP6) (Fujita et al. 1995) mediates the intracellular binding and movement of bile acids (Kurz et al. 2003) to the basolateral membrane where organic solute transporters (OSTs) export bile acids and salts into the portal circulation to be returned to the liver.

Literature References
PubMed ID Title Journal Year
7588781 Molecular cloning, expression, and characterization of a human intestinal 15-kDa protein

Fujita, M, Fujii, H, Kanda, T, Sato, E, Hatakeyama, K, Ono, T

Eur J Biochem 1995
12486725 Insights into the bile acid transportation system: the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures

Kurz, M, Brachvogel, V, Matter, H, Stengelin, S, Thüring, H, Kramer, W

Proteins 2003
Participants
Participates
Orthologous Events
Authored
Reviewed
Created
Cite Us!