Cytosolic ileal bile acid binding protein (IBABP, FABP6) (Fujita et al. 1995) mediates the intracellular binding and movement of bile acids (Kurz et al. 2003) to the basolateral membrane where organic solute transporters (OSTs) export bile acids and salts into the portal circulation to be returned to the liver. It is assumed that bile acids dissociate from FABP6 by an as-yet unknown mechanism before OSTs transport them across the basolateral membrane.
Fujita, M, Fujii, H, Kanda, T, Sato, E, Hatakeyama, K, Ono, T
Kurz, M, Brachvogel, V, Matter, H, Stengelin, S, Thüring, H, Kramer, W
© 2021 Reactome
