Expression of MESP1 in cardiogenesis

Stable Identifier
R-HSA-9733754
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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Expression of MESP1 in cardiogenesis
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The MESP1 gene is transcribed to yield mRNA and the mRNA is translated to yield MESP1 protein. In lateral plate mesoderm, EOMES and T (TBXT, Brachyury) activate transcription of MESP1 (inferred from mouse homologs). MESP1 is the first observed marker of cardiac progenitor cells.
Literature References
PubMed ID Title Journal Year
26783251 A comprehensive gene expression analysis at sequential stages of in vitro cardiac differentiation from isolated MESP1-expressing-mesoderm progenitors

den Hartogh, SC, Mummery, CL, Wolstencroft, K, Passier, R

Sci Rep 2016
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
EOMES:WDR5:KAT2A:TBXT:MESP1 gene [nucleoplasm] (Homo sapiens)
Inferred From
Expression of Mesp1 in cardiogenesis (Mus musculus)
Authored
May, B  (2021-06-07)
Created
May, B  (2021-06-10)
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