nsp6 localizes to the nuclear envelope

Stable Identifier
R-HSA-9731262
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Severe acute respiratory syndrome coronavirus 2
Compartment
endoplasmic reticulum membrane, nuclear envelope
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
nsp6 localizes to the nuclear envelope
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The cell's outer nuclear membrane is continuous with the endoplasmic reticulum membrane (ER). SARS-CoV-2 nsp6 has six transmembrane domains and shows ER and perinuclear localization (Lee et al, 2021).
Literature References
PubMed ID Title Journal Year
33766124 Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor

Huang, W, van de Leemput, J, Lee, JG, Han, Z, Kane, MA, Lee, H

Cell Biosci 2021
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Authored
Stephan, R  (2021-05-17)
Created
Stephan, R  (2021-05-19)
Cite Us!