Nucleoprotein is SUMOylated

Stable Identifier
R-HSA-9729307
Type
Reaction
Species
Homo sapiens
Related Species
Severe acute respiratory syndrome coronavirus 2
Compartment
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This COVID-19 event has been created by a combination of computational inference (see https://reactome.org/documentation/inferred-events) from SARS-CoV-1 data and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway.

N protein is sumoylated at a lysine residue. Abolition of sumoylation of nucleoprotein significantly decreases homo-oligomerisation of the protein (Li et al, 2005)

Literature References
PubMed ID Title Journal Year
15848177 Sumoylation of the nucleocapsid protein of severe acute respiratory syndrome coronavirus

Liu, DX, Xiao, H, Li, FQ, Tam, JP

FEBS Lett. 2005
Participants
Participates
Inferred From
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
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