Reactome | TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13

TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13

Stable Identifier

R-HSA-9728729

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

plasma membrane

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TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13

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Upon binding GTP, the gustducin alpha subunit (GNAT3:GTP) and the beta-gamma subcomplex (GNB1,3:GNG13) dissociate from the sweet receptor-gustducin complex (sweet tastant:TAS1R2:TAS1R3:GNAT3:GTP:GNB1,3:GNG13) (inferred from the closely related transducin complex).

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