Reactome | keratinocyte of spinosum layer of epidermis

Stable Identifier

R-HSA-9727360

Type

Cell

Species

Homo sapiens

Synonyms

keratinocyte of skin epidermis stratum spinosum

Locations in the PathwayBrowser

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Cytology

Organ

skin of body (UBERON:0002097)

Tissue

skin epidermis (UBERON:0001003)

Tissue Layer

stratum spinosum of epidermis (UBERON:0002026)

Cell Type

keratinocyte (CL:0000312)

Markers

Protein

- E-FABP induces differentiation in normal human keratinocytes and modulates the differentiation process in psoriatic keratinocytes in vitro.Exp Dermatol22,255-61(2013)Lotti, R., Marconi, A., Pincelli, C., Saltari, A., Palazzo, E., Truzzi, F., Coppini, M., Petrachi, T., Dallaglio, K.
- A histological and immunohistochemical study on chronic irritant contact dermatitis.Am J Contact Dermat9,23-8(1998)van Haelst, U., van der Valk, PG., van de Kerkhof, PC., Le, TK., Schalkwijk, J.

- Impaired stratum corneum hydration in mice lacking epidermal water channel aquaporin-3.J Biol Chem277,17147-53(2002)Ma, T., Verkman, AS., Verbavatz, JM., Hara, M., Sougrat, R.
- PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data.Database (Oxford)2019,null(2019)Franzén, O., Gan, LM., Björkegren, JLM.
- Functional expression of AQP3 in human skin epidermis and reconstructed epidermis.J Invest Dermatol118,678-85(2002)Gondran, C., Dumas, M., Gobin, R., Morand, M., Verbavatz, JM., Bonté, F., Barré, P., Sougrat, R.
- Osmotic stress up-regulates aquaporin-3 gene expression in cultured human keratinocytes.Biochim Biophys Acta1522,82-8(2001)Ota, Y., Sugiyama, Y., Inoue, S., Hara, M.

- Role of keratin 24 in human epidermal keratinocytes.PLoS One12,e0174626(2017)Landeck, L., Wang, P., Zheng, M., Cai, SQ., Man, XY., Li, W., Min, M., Chen, JQ., Chen, XB.
- The expression pattern of keratin 24 in tissue-engineered dermo-epidermal human skin substitutes in an in vivo model.Pediatr Surg Int34,237-244(2018)Reichmann, E., Böttcher-Haberzeth, S., Meuli, M., Biedermann, T., Michalak, K., Klar, AS.

RNA

- Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution.Cell Rep25,871-883(2018)Song, JS., Neuhaus, IM., Ghadially, R., Vaske, CJ., Purdom, E., Liao, W., Lee, J., Golovato, J., Gray, JW., Fassett, MS., Benz, SC., Gray, M., Kim, EA., Cho, RJ., Grekin, RC., Yu, SS., Cheng, JB., Mully, T., Mauro, TM., Finnegan, AI., Kwon, S., Perez White, BE., Harirchian, P., Paus, R., Sedgewick, AJ., Sbitany, H.
- Single-cell RNA sequencing of human epidermis identifies Lunatic fringe as a novel regulator of the stem cell compartment.Stem Cell Reports18,2047-2055(2023)Philippeos, C., Haniffa, M., Watt, FM., Ganier, C., Louis, B., Ali, S., Reynolds, G., Zijl, S., Negri, VA.
- Transcriptional profiling of epidermal keratinocytes: comparison of genes expressed in skin, cultured keratinocytes, and reconstituted epidermis, using large DNA microarrays.J Invest Dermatol121,1459-68(2003)De Wever, B., Ramphal, P., Blumenberg, M., Rosdy, M., Gazel, A., Hosein, N., Lee, B., Tornier, C., Tomic-Canic, M.

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