mRNA8 is translated to protein 8

Stable Identifier
R-HSA-9727305
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Severe acute respiratory syndrome coronavirus 2
Compartment
cytosol, endoplasmic reticulum lumen
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
mRNA8 is translated to protein 8
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The open reading frame 8 (ORF8) of SARS-Cov-2 mRNA8 has a length of 366 nt and encodes the 121 aa preprotein 8. After cleavage of the signal peptide, it has a final length of 106 aa (Wu et al, 2020). In HEK 293 T cells, protein 8 was present in the ER (Lee et al, 2021).
Literature References
PubMed ID Title Journal Year
32015508 A new coronavirus associated with human respiratory disease in China

Song, ZG, Liu, Y, Yuan, ML, Tian, JH, Zhang, YL, Dai, FH, Zhang, YZ, Wu, F, Pei, YY, Chen, YM, Yu, B, Xu, L, Zheng, JJ, Zhao, S, Tao, ZW, Wang, QM, Holmes, EC, Wang, W, Hu, Y

Nature 2020
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Authored
Stephan, R  (2021-04-13)
Reviewed
Gillespie, ME  (2022-05-10)
Created
Stephan, R  (2021-04-15)
Cite Us!