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p-S354 ZC3HC1 [nucleoplasm]
Stable Identifier
R-HSA-9724996
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Nuclear-interacting partner of ALK, NIPA_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ALK in cancer (Homo sapiens)
Signaling by ALK fusions and activated point mutants (Homo sapiens)
Nuclear events stimulated by ALK signaling in cancer (Homo sapiens)
MAPK1 phsophorylates ZC3HCF1 in a NPM-ALK-dependent manner (Homo sapiens)
NPM1p-7Y ALK fusion dimer:CUL1:RBX1:SKP1:p-S354 ZC3HC1 [nucleoplasm] (Homo sapiens)
CUL1:RBX1:SKP1:p-S354 ZC3HC1 [nucleoplasm] (Homo sapiens)
p-S354 ZC3HC1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86WB0 ZC3HC1
Gene Names
ZC3HC1, NIPA, HSPC216
Chain
initiator methionine:, chain:2-502
Reference Genes
BioGPS Gene:51530 ZC3HC1
COSMIC (genes):ZC3HC1 ZC3HC1
CTD Gene:51530 ZC3HC1
dbSNP Gene:51530 ZC3HC1
ENSEMBL:ENSG00000091732 ZC3HC1
ENSEMBL_homo_sapiens_GENE:ENSG00000091732.17 ZC3HC1
HGNC:29913 ZC3HC1
KEGG Gene (Homo sapiens):51530 ZC3HC1
Monarch:51530 ZC3HC1
NCBI Gene:51530 ZC3HC1
OMIM:619746 ZC3HC1
UCSC:Q86WB0 ZC3HC1
Reference Transcript
RefSeq:NM_016478.4 ZC3HC1
RefSeq:NM_001282191.1 ZC3HC1
RefSeq:NM_001282190.1 ZC3HC1
Other Identifiers
11756960_a_at
17062832
223163_PM_s_at
223163_s_at
3072369
3072370
3072371
3072372
3072379
3072380
3072381
3072382
3072383
3072384
3072385
3072392
3072394
3072395
3072400
3072401
3072406
3072407
51530
78439_at
8142899
A_23_P215088
GE55749
GO:0005515
GO:0005634
GO:0005635
GO:0005654
GO:0007049
GO:0008270
GO:0012501
GO:0016567
GO:0019901
GO:0023052
GO:0031965
GO:0036211
GO:0043226
GO:0046872
GO:0051301
GO:2001240
HMNXSV003015450
ILMN_1761479
PH_hs_0001305
g12652870_3p_a_at
Participates
as a component of
CUL1:RBX1:SKP1:p-S354 ZC3HC1 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
ZC3HC1 [nucleoplasm]
Modified Residues
Name
O-phospho-L-serine at 354
Coordinate
354
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_057562.3
,
NP_001269120.1
,
NP_001269119.1
OpenTargets
ENSG00000091732
HPA
ENSG00000091732-ZC3HC1
GeneCards
Q86WB0
Ensembl
ENST00000358303
,
ENSP00000351052
,
ENSP00000353933
,
ENSG00000091732
,
ENST00000360708
PRO
Q86WB0
Pharos - Targets
Q86WB0
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P53350 PLK1
4
PLK1 [nucleoplasm]
(R-HSA-156720)
p-T210-PLK1 [cytosol]
(R-HSA-3000318)
p-T210-PLK1 [nucleoplasm]
(R-HSA-3002800)
PLK1 [cytosol]
(R-HSA-164603)
0.643
5
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