RANBP2(1-867)-p-7Y-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9718443
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
E3 SUMO-protein ligase RanBP2 ecNumber evidence="29 31 33 37 44"2.3.2.-/ecNumber, RBP2_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
18701132 An inflammatory myofibroblastic tumor in liver with ALK and RANBP2 gene rearrangement: combination of distinct morphologic, immunohistochemical, and genetic features

Chen, ST, Lee, JC

Hum. Pathol. 2008
21164297 Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK

Wang, WL, Hornick, JL, Roy, A, Coffin, CM, Mariño-Enríquez, A, Lazar, AJ, Lopez-Terrada, D, Fletcher, CD

Am. J. Surg. Pathol. 2011
27874193 ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma

Fletcher, JA, Hornick, JL, Lee, CT, Ou, WB, Mariño-Enríquez, A, Li, CF, Lee, JC, Zhu, MJ, Huang, HY

J. Pathol. 2017
External Reference Information
External Reference
Gene Names
RANBP2, NUP358
Chain
chain:1-3224
Reference Transcript
Other Identifiers
11722814_s_at
11722815_at
11722816_at
11754283_s_at
11758005_s_at
16884126
201711_PM_x_at
201711_x_at
201712_PM_s_at
201712_s_at
201713_PM_s_at
201713_s_at
226922_PM_at
226922_at
2492220
2492221
2492223
2492290
2492297
2492302
2492303
2492304
2492305
2492307
2492308
2492310
2492312
2492313
2492315
2492316
2492317
2498744
2498745
2498746
2498747
2498748
2498750
2498751
2498752
2498753
2498755
2498757
2498758
2498759
2498763
2498764
2498765
2499126
2499159
2499160
2499162
2499163
2499164
2499165
2499166
2499167
2499169
2499170
2499171
2499173
2499175
2499177
2499178
2499179
2499180
2499181
2499182
2499183
2499184
2499185
2499186
2499187
2499188
2499189
2499190
2499191
2499193
2499194
2499195
2499196
2499197
2499201
2499202
2499203
2499204
2499205
2499206
2499207
2499208
2499209
2499210
2499211
2499235
2499236
2499237
2499619
2499620
2499621
2499623
2499624
2499625
2499626
2499631
2499633
2499634
2499635
2499637
2499640
2499641
2499642
2499643
2499644
2499645
2499648
2499649
2499650
2563430
2563431
2563432
2563434
2563436
2563437
2563439
2563440
2563442
2563444
2563446
2563447
2563448
2563452
2563455
2563456
2563458
2569096
2569097
2569098
2569102
2569103
2569104
2569105
2569107
2569109
2569110
2569111
2569112
2569116
2569117
2569118
2569119
2569120
2570484
2570486
2570488
2570490
2570491
2570493
2570494
2570495
2570498
2570499
2570500
2570501
2570503
2570510
2570511
2570512
2570513
2570515
2570516
2570517
2570556
2570557
2570559
2570561
2570564
2570566
2570567
2570569
2570570
2570571
2570574
2570576
2570577
2570578
2570580
2570588
2570589
2570590
2570591
2570593
2570594
2570595
2571300
2571302
2571303
2571305
2571306
2571308
2571309
2571310
2571313
2571315
2571316
2571317
2571319
2571326
2571327
2571328
2571329
2571331
2571332
2571333
32788_at
51177_at
5903
8044161
8044263
8044304
8054414
8054532
8054557
8054676
A_14_P113906
A_23_P131664
A_24_P350890
A_33_P3272390
A_33_P3308740
D42063_at
GE61553
GE80234
GO:0000413
GO:0001975
GO:0003723
GO:0003755
GO:0003824
GO:0005096
GO:0005515
GO:0005634
GO:0005635
GO:0005642
GO:0005643
GO:0005654
GO:0005737
GO:0005829
GO:0005975
GO:0006111
GO:0006457
GO:0006607
GO:0006807
GO:0006886
GO:0006913
GO:0015031
GO:0016020
GO:0016740
GO:0016853
GO:0016925
GO:0019789
GO:0031267
GO:0031965
GO:0033133
GO:0036211
GO:0042405
GO:0043170
GO:0043226
GO:0043231
GO:0044238
GO:0044614
GO:0044615
GO:0044877
GO:0046872
GO:0046907
GO:0051028
GO:0051168
GO:0051642
GO:0061665
GO:0098772
GO:0106068
GO:0140096
GO:1990723
HMNXSV003021186
HMNXSV003037067
Hs.199179.0.S1_3p_s_at
Hs.28248.0.A1_3p_at
ILMN_1654866
ILMN_2320574
PH_hs_0011701
TC02000668.hg
g6382078_3p_a_at
g924266_3p_a_at
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 1058 to 1620 at 868 from UniProt:Q9UM73 ALK
Coordinate
868
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1358
Coordinate
1358
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
COSMIC
OpenTargets
GeneCards
PRO
Pharos - Targets
Orphanet
HMDB Protein
Interactors (10)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P62826 RAN  2 0.764 4
 UniProt:P63279 UBE2I  9 0.752 4
 UniProt:O60260 PARK2  3 0.639 11
 UniProt:Q921C5-1 BICD2      0.633 4
 UniProt:P46060 RANGAP1  3 0.623 4
 UniProt:Q9BPX7 CG025      0.544 3
 UniProt:Q5S007 LRRK2  1 0.527 3
 UniProt:Q9UBU9 NXF1  2 0.527 2
 UniProt:P13569 CFTR  17 0.483 6
 UniProt:P04626 ERBB2  20 0.463 3
Cite Us!