Reactome | p-7Y ALK V1180L dimer [plasma membrane]

p-7Y ALK V1180L dimer [plasma membrane]

Stable Identifier

R-HSA-9715316

Type

Complex

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
  - Signaling by ALK in cancer (Homo sapiens)
    - Signaling by ALK fusions and activated point mutants (Homo sapiens)
      - Autophosphorylation of point mutants of ALK (Homo sapiens)
        
        p-7Y ALK point mutant dimers [plasma membrane] (Homo sapiens)
        
        p-7Y kinase domain ALK mutant dimers [plasma membrane] (Homo sapiens)
        
        p-7Y ALK V1180L dimer [plasma membrane] (Homo sapiens)

Participants

components

x 2 p-7Y ALK V1180L [plasma membrane] (Homo sapiens)

Participates

as a member of

p-7Y kinase domain ALK mutant dimers [plasma membrane] (Homo sapiens)

Disease

Name	Identifier	Synonyms
lung squamous cell carcinoma	DOID:3907	squamous cell carcinoma of lung (disorder), Epidermoid cell carcinoma of the lung

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