Reactome | MSI2 [cytosol]

MSI2 [cytosol]

Stable Identifier

R-HSA-9715155

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RHOBTB GTPase Cycle (Homo sapiens)
        
        RHOBTB2 GTPase cycle (Homo sapiens)
        
        RHOBTB2 binds interacting proteins at the endosome membrane (Homo sapiens)
        
        RHOBTB2 interacting proteins [cytosol] (Homo sapiens)
        
        MSI2 [cytosol] (Homo sapiens)
        
        RHOBTB2:GTP:RHOBTB2 interacting proteins [endosome membrane] (Homo sapiens)
        
        RHOBTB2 interacting proteins [cytosol] (Homo sapiens)
        
        MSI2 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96DH6 MSI2

Gene Names

MSI2

Chain

initiator methionine:, chain:1-328

Reference Genes

BioGPS Gene:124540 MSI2

COSMIC (genes):MSI2 MSI2

CTD Gene:124540 MSI2

dbSNP Gene:124540 MSI2

ENSEMBL:ENSG00000153944 MSI2

ENSEMBL_homo_sapiens_GENE:ENSG00000153944.12 MSI2

HGNC:18585 MSI2

KEGG Gene (Homo sapiens):124540 MSI2

Monarch:124540 MSI2

NCBI Gene:124540 MSI2

OMIM:607897 MSI2

UCSC:Q96DH6 MSI2

Reference Transcript

Other Identifiers

11732708_a_at

11733375_a_at

11746497_a_at

11760324_a_at

11760325_x_at

124540

1552364_PM_s_at

1552364_s_at

16836375

225233_PM_at

225233_at

225237_PM_s_at

225237_s_at

225238_PM_at

225238_at

225240_PM_s_at

225240_s_at

226134_PM_s_at

226134_s_at

243010_PM_at

243010_at

243579_PM_at

243579_at

3728148

3728149

3728151

3728152

3728153

3728154

3728158

3728183

3728205

3728237

3728264

3728273

3728284

3728292

3728293

3728294

3728299

3728311

3728313

3728314

3728315

3728316

3728317

3728318

3728319

3728320

3728321

3728322

50082_at

52065_s_at

64973_at

74924_at

8008682

87761_at

87764_g_at

A_14_P111435

A_14_P117686

A_14_P127656

A_14_P128953

A_14_P135592

A_23_P369479

A_23_P44195

GE88536

GO:0003676

GO:0003723

GO:0003727

GO:0003729

GO:0005515

GO:0005737

GO:0005829

GO:0005844

GO:0006417

GO:0007417

GO:0008266

GO:0030154

GO:0042802

GO:0043226

GO:0043231

GO:0048856

GO:0048864

HMNXSV003039332

HMNXSV003053354

HMNXSV003057374

Hs.103512.0.A1_3p_at

Hs.42179.0.A1_3p_at

Hs.42179.0.A2_3p_a_at

Hs.42179.0.A3_3p_at

Hs.42640.0.A1_3p_at

Hs2.103512.1.S1_3p_s_at

ILMN_1713088

ILMN_1804448

ILMN_2302075

PH_hs_0022875

TC17000705.hg

Participates

as a member of

RHOBTB2 interacting proteins [cytosol] (Homo sapiens)

Inferred To

MSI2 [cytosol] (Canis familiaris)

MSI2 [cytosol] (Gallus gallus)

MSI2 [cytosol] (Sus scrofa)

msi [cytosol] (Drosophila melanogaster)

Msi2 [cytosol] (Mus musculus)

Msi2 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_620412.1, NP_733839.1

OpenTargets

ENSG00000153944

GeneCards

Q96DH6

HPA

ENSG00000153944-MSI2

Ensembl

ENST00000284073, ENSP00000462264, ENSG00000153944, ENSP00000313616, ENST00000579180, ENST00000322684, ENSP00000284073, ENST00000674964, ENSP00000502137

PRO

Q96DH6

Pharos - Targets

Q96DH6

PDB

6C8U, 6DBP, 6NTY

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.59	4
UniProt:Q9Y5J6 TIMM10B	1	4xHC-TIMM10B [mitochondrial inner membrane] (R-HSA-1252043)	0.499	2