Reactome | ESYT1 [plasma membrane]

ESYT1 [plasma membrane]

Stable Identifier

R-HSA-9715081

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Extended synaptotagmin-1, ESYT1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9BSJ8 ESYT1

Gene Names

ESYT1, FAM62A, KIAA0747, MBC2

Chain

chain:1-1104

Reference Genes

BioGPS Gene:23344 ESYT1

COSMIC (genes):ESYT1 ESYT1

CTD Gene:23344 ESYT1

dbSNP Gene:23344 ESYT1

ENSEMBL:ENSG00000139641 ESYT1

ENSEMBL_homo_sapiens_GENE:ENSG00000139641.13 ESYT1

HGNC:29534 ESYT1

KEGG Gene (Homo sapiens):23344 ESYT1

Monarch:23344 ESYT1

NCBI Gene:23344 ESYT1

UCSC:Q9BSJ8 ESYT1

Reference Transcript

Other Identifiers

11716288_s_at

16752495

208858_PM_s_at

208858_s_at

23344

244234_PM_at

244234_at

3417039

3417372

3417373

3417374

3417375

3417376

3417378

3417379

3417380

3417381

3417382

3417383

3417384

3417386

3417388

3417390

3417392

3417394

3417395

3417396

3417397

3417399

3417400

3417401

3417402

3417403

3417404

3417405

3417407

3417409

3417410

3417412

3417414

3417415

3417416

3417417

3417418

3417419

3417420

3417421

3417422

3417423

3417424

3417425

38424_at

64517_at

68197_at

7956166

A_14_P111701

A_14_P127427

A_23_P150852

GE53458

GO:0005215

GO:0005509

GO:0005515

GO:0005544

GO:0005783

GO:0005789

GO:0005886

GO:0006869

GO:0008289

GO:0008429

GO:0015914

GO:0016020

GO:0031210

GO:0031234

GO:0035091

GO:0042802

GO:0043226

GO:0046872

GO:0061024

GO:0061817

GO:0120009

GO:0120014

HMNXSV003004947

Hs.190160.0.A1_3p_at

ILMN_1761159

PH_hs_0000885

TC12000504.hg

g13436457_3p_a_at

Participates

as a candidate of

Other forms of this molecule

ESYT1 [endoplasmic reticulum membrane]

Inferred To

ESYT1 [plasma membrane] (Canis familiaris)

ESYT1 [plasma membrane] (Gallus gallus)

ESYT1 [plasma membrane] (Mus musculus)

ESYT1 [plasma membrane] (Rattus norvegicus)

ESYT1 [plasma membrane] (Sus scrofa)

FAM62A [plasma membrane] (Bos taurus)

esyt-2 [plasma membrane] (Caenorhabditis elegans)

Esyt2 [plasma membrane] (Drosophila melanogaster)

esyt1 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_056107.1, NP_001171725.1

OpenTargets

ENSG00000139641

GeneCards

Q9BSJ8

HPA

ENSG00000139641-ESYT1

Ensembl

ENST00000267113, ENSG00000139641, ENSP00000377612, ENSP00000267113, ENST00000394048

PRO

Q9BSJ8

Pharos - Targets

Q9BSJ8

HMDB Protein

HMDBP07671

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.564	2
UniProt:Q8TC12 RDH11	1	RDH11 [endoplasmic reticulum membrane] (R-HSA-975645)	0.508	2
UniProt:P22309 UGT1A1	7	UGT1A1 [endoplasmic reticulum membrane] (R-HSA-159156) UGT1A1 S376F [endoplasmic reticulum membrane] (R-HSA-5604983) UGT1A1 Q331* [endoplasmic reticulum membrane] (R-HSA-5605030) UGT1A1 G309E [endoplasmic reticulum membrane] (R-HSA-5604963) UGT1A1 R341* [endoplasmic reticulum membrane] (R-HSA-5604994) UGT1A1 Y293Mfs*69 [endoplasmic reticulum membrane] (R-HSA-5604959) UGT1A1 L15R [endoplasmic reticulum membrane] (R-HSA-5604984)	0.499	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	10

Cite Us!