Reactome | DBN1 [cytosol]

DBN1 [cytosol]

Stable Identifier

R-HSA-9714666

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Drebrin, DREB_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q16643 DBN1

Gene Names

DBN1, D0S117E

Chain

initiator methionine:, chain:2-649

Reference Genes

BioGPS Gene:1627 DBN1

COSMIC (genes):DBN1 DBN1

CTD Gene:1627 DBN1

dbSNP Gene:1627 DBN1

ENSEMBL:ENSG00000113758 DBN1

ENSEMBL_homo_sapiens_GENE:ENSG00000113758.14 DBN1

HGNC:2695 DBN1

KEGG Gene (Homo sapiens):1627 DBN1

Monarch:1627 DBN1

NCBI Gene:1627 DBN1

OMIM:126660 DBN1

UCSC:Q16643 DBN1

Reference Transcript

Other Identifiers

11729702_a_at

11729703_a_at

11732120_a_at

1627

17003261

202806_PM_at

202806_at

217025_PM_s_at

217025_s_at

2888799

2888801

2888802

2888803

2888804

2888805

2888807

2888808

2888810

2888811

2888812

2888813

2888816

2888817

2888819

2888821

2888823

2888824

2888825

2888828

2888829

2888830

2888831

2888832

2888833

2888834

37981_at

63670_s_at

8116051

A_23_P156284

A_24_P97849

GE79428

GO:0001701

GO:0003779

GO:0005515

GO:0005522

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005911

GO:0005921

GO:0005938

GO:0007010

GO:0007015

GO:0007399

GO:0008092

GO:0010643

GO:0010644

GO:0014069

GO:0015629

GO:0016020

GO:0023052

GO:0030154

GO:0030425

GO:0030426

GO:0030863

GO:0031915

GO:0032507

GO:0034330

GO:0042641

GO:0042995

GO:0043226

GO:0045211

GO:0045296

GO:0048168

GO:0048699

GO:0048856

GO:0050773

GO:0051220

GO:0061003

GO:0061351

GO:0070161

GO:0098978

GO:0099524

GO:1902685

HMNXSV003053472

Hs.89434.1.S1_3p_a_at

ILMN_1757270

ILMN_1769926

PH_hs_0004982

TC05002108.hg

U00802_s_at

g4758123_3p_at

Participates

as a candidate of

Cross References

RefSeq

XP_005265884.1, XP_016864629.1, NP_543157.1, NP_004386.2

OpenTargets

ENSG00000113758

GeneCards

Q16643

HPA

ENSG00000113758-DBN1

Ensembl

ENSP00000377195, ENSP00000308532, ENSP00000292385, ENST00000292385, ENST00000309007, ENSG00000113758, ENST00000393565

PRO

Q16643

Pharos - Targets

Q16643

PDB

5Y1Z, 5ZZ9

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61073 CXCR4	1	CXCR4 [plasma membrane] (R-HSA-2980772)	0.702	5
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.674	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	20
UniProt:O35889 Afdn	2	Afadin [cytosol] (R-RNO-433723) Afdn [cytosol] (R-RNO-418342)	0.576	3
UniProt:Q14247 CTTN	2	CTTN [cytosol] (R-HSA-201894) p-S113-CTTN [cytosol] (R-HSA-442842)	0.527	2
UniProt:P08050 Gja1	10	Cx43 [plasma membrane] (R-RNO-191661) Connexin 43 [Golgi membrane] (R-RNO-190650) Cx43 [endoplasmic reticulum membrane] (R-RNO-190688) Gja1 [Golgi membrane] (R-RNO-190649) Gja1 [endoplasmic reticulum membrane] (R-RNO-190654) Gja1 [lysosomal membrane] (R-RNO-196173) phospho-Gja1 [plasma membrane] (R-RNO-191657) Gja1 [plasma membrane] (R-RNO-158058) Cx43 [Golgi-associated vesicle membrane] (R-RNO-190646) Gja1 [Golgi-associated vesicle membrane] (R-RNO-190544)	0.489	2
UniProt:P60484 PTEN	20	K48polyUb-PTEN [cytosol] (R-HSA-8874327) PolyUb-PTEN [nucleoplasm] (R-HSA-6782515) PTEN H93R [cytosol] (R-HSA-2318524) PTEN C124R [cytosol] (R-HSA-2317439) PTEN H93Y [cytosol] (R-HSA-2318520) PTEN R130G [cytosol] (R-HSA-2317339) PTEN H93D [cytosol] (R-HSA-2318550) PTEN R130L [cytosol] (R-HSA-2317430) PTEN H93A [cytosol] (R-HSA-2318544) PTEN G129E [cytosol] (R-HSA-2318509) PTEN S170N [cytosol] (R-HSA-2318408) PTEN R173P [cytosol] (R-HSA-2317480) PTEN R130Q [cytosol] (R-HSA-2317416) PTEN H93Q [cytosol] (R-HSA-2318565) PTEN G129R [cytosol] (R-HSA-2318501) PTEN H123Y [cytosol] (R-HSA-2318469) PTEN S170R [cytosol] (R-HSA-2318437) PTEN R173C [cytosol] (R-HSA-2317478) PTEN R173H [cytosol] (R-HSA-2317473) PTEN C124S [cytosol] (R-HSA-2317379)	0.471	5

Cite Us!