RAC2 binds effectors at the mitochondrial outer membrane

Stable Identifier
R-HSA-9714477
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
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RAC2 interacts with several effectors localized at the mitochondrial outer membrane. Since RAC2 localization at the mitochondrial outer membrane and its association with mitochondrial proteins has not been fully established, these effectors are annotated as candidates:
ARMCX3 (Bagci et al. 2020)
MTX1 (Capala et al. 2015)
SAMM50 (Capala et al. 2015)

Literature References
PubMed ID Title Journal Year
31871319 Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

Bagci, H, Sriskandarajah, N, Robert, A, Boulais, J, Elkholi, IE, Tran, V, Lin, ZY, Thibault, MP, Dubé, N, Faubert, D, Hipfner, DR, Gingras, AC, Cote, JF

Nat. Cell Biol. 2020
26016997 Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2

Capala, ME, Maat, H, Bonardi, F, van den Boom, V, Kuipers, J, Vellenga, E, Giepmans, BN, Schuringa, JJ

PLoS One 2015
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