RHOC activates endoplasmic reticulum effectors

Stable Identifier
R-HSA-9714361
Type
Reaction [binding]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
ReviewStatus
5/5
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RHOC activates endoplasmic reticulum effectors
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Based on the high throughput screen conducted by Bagci et al. 2020, constitutively active RHOC binds to the following candidate effectors, known to reside at the endoplasmic reticulum membrane:
LBR (Bagci et al. 2020)
LMAN1 (Bagci et al. 2020)
MACO1 (Bagci et al. 2020)
PGRMC2 (Bagci et al. 2020)
STX5 (Bagci et al. 2020)
VAPB (Bagci et al. 2020)

Literature References
PubMed ID Title Journal Year
31871319 Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

Tran, V, Gingras, AC, Elkholi, IE, Robert, A, Boulais, J, Faubert, D, Dubé, N, Hipfner, DR, Cote, JF, Lin, ZY, Bagci, H, Sriskandarajah, N, Thibault, MP

Nat. Cell Biol. 2020
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Authored
Orlic-Milacic, M  (2020-07-14)
Reviewed
Fort, P  (2021-02-05)
Created
Orlic-Milacic, M  (2021-02-10)
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