Reactome | TEX2 [endoplasmic reticulum membrane]

TEX2 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-9714346

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Testis-expressed protein 2

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RHOA GTPase cycle (Homo sapiens)
        
        RHOA binds effectors at the ER membrane (Homo sapiens)
        
        RHOA endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Homo sapiens)
        
        TEX2 [endoplasmic reticulum membrane] (Homo sapiens)
        
        RHOA:GTP:RHOA endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Homo sapiens)
        
        RHOA endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Homo sapiens)
        
        TEX2 [endoplasmic reticulum membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8IWB9 TEX2

Gene Names

TEX2, KIAA1738, TMEM96

Chain

chain:1-1127

Reference Genes

BioGPS Gene:55852 TEX2

COSMIC (genes):TEX2 TEX2

CTD Gene:55852 TEX2

dbSNP Gene:55852 TEX2

ENSEMBL:ENSG00000136478 TEX2

HGNC:30884 TEX2

KEGG:hsa:55852 TEX2

Monarch:55852 TEX2

NCBI Entrez Gene:55852 TEX2

OMIM:619929 TEX2

UCSC:Q8IWB9 TEX2

Reference Transcript

Other Identifiers

11722041_s_at

16847795

218099_PM_at

218099_at

3766717

3766718

3766719

3766720

3766721

3766722

3766723

3766724

3766725

3766726

3766727

3766728

3766729

3766730

3766731

3766732

3766734

3766741

3766743

3766744

3766749

3766750

3766751

3766765

3766766

3766767

3766768

3766769

3766771

3766773

3766775

3766782

44717_at

55852

8017582

86351_at

A_23_P4036

GE61006

GE82383

GO:0005634

GO:0005783

GO:0005789

GO:0006629

GO:0006665

GO:0006869

GO:0007165

GO:0008289

GO:0016020

GO:0031965

HMNXSV003047923

ILMN_1731181

PH_hs_0001496

PH_hs_0031503

TC17001797.hg

g8923803_3p_at

Participates

as a candidate of

RHOA endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

Tex2 [endoplasmic reticulum membrane] (Mus musculus)

Tex2 [endoplasmic reticulum membrane] (Rattus norvegicus)

tex2.2 [endoplasmic reticulum membrane] (Xenopus tropicalis)

TEX2 [endoplasmic reticulum membrane] (Bos taurus)

TEX2 [endoplasmic reticulum membrane] (Canis familiaris)

TEX2 [endoplasmic reticulum membrane] (Sus scrofa)

Cross References

RefSeq

XP_054172634.1, XP_054172638.1, XP_054172633.1, XP_054172637.1, XP_054172636.1, NP_060939.3, XP_054172632.1, XP_047292350.1, XP_047292351.1, NP_001275661.1, XP_047292352.1, NP_001275662.1, XP_047292348.1, XP_011523301.1, XP_011523300.1, XP_047292349.1

OpenTargets

ENSG00000136478

ENSEMBL

ENST00000583097, ENSP00000462665, ENST00000258991, ENST00000584379, ENSG00000136478, ENSP00000463001, ENSP00000258991

HPA

ENSG00000136478-TEX2

GeneCards

TEX2

PRO

Q8IWB9

Pharos - Targets

Q8IWB9

GlyGen

Q8IWB9

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NP91 SLC6A20	2	SLC6A20 [plasma membrane] (R-HSA-352058) SLC6A20 T199M [plasma membrane] (R-HSA-5660705)	0.527	2
UniProt:Q9H2J7 SLC6A15	1	SLC6A15 [plasma membrane] (R-HSA-352060)	0.527	2