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TMPO [cytosol]
Stable Identifier
R-HSA-9714330
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 binds effectors at the plasma membrane (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
CDC42:GTP:CDC42 effectors [plasma membrane] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 binds effectors at the plasma membrane (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RAC1:GTP:RAC1 effectors [plasma membrane] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 binds effectors at the plasma membrane (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 binds effectors at the plasma membrane (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA binds effectors at the plasma membrane (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC binds effectors at the plasma membrane (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOC:GTP:RHOC effectors [plasma membrane] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOD GTPase cycle (Homo sapiens)
RHOD binds effectors at the plasma membrane (Homo sapiens)
RHOD plasma membrane effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOD:GTP:RHOD plasma membrane effectors [plasma membrane] (Homo sapiens)
RHOD plasma membrane effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOF GTPase cycle (Homo sapiens)
RHOF binds effectors at the plasma membrane (Homo sapiens)
RHOF effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOF:GTP:RHOF effectors [plasma membrane] (Homo sapiens)
RHOF effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOG GTPase cycle (Homo sapiens)
RHOG binds effectors at the plasma membrane (Homo sapiens)
RHOG plasma membrane effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Homo sapiens)
RHOG plasma membrane effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOJ GTPase cycle (Homo sapiens)
RHOJ binds effectors at the plasma membrane (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
RHOJ:GTP:RHOJ effectors [plasma membrane] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
TMPO [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P42167 TMPO
Gene Names
TMPO, LAP2
Chain
chain:1-454, peptide:1-50, peptide:33-37
Reference Genes
BioGPS Gene:7112 TMPO
COSMIC (genes):TMPO TMPO
CTD Gene:7112 TMPO
dbSNP Gene:7112 TMPO
ENSEMBL:ENSG00000120802 TMPO
ENSEMBL_homo_sapiens_GENE:ENSG00000120802.14 TMPO
KEGG Gene (Homo sapiens):7112 TMPO
Monarch:7112 TMPO
NCBI Gene:7112 TMPO
OMIM:188380 TMPO
UCSC:P42167 TMPO
Reference Transcript
RefSeq:NM_001307975.1 TMPO
RefSeq:NM_001032283.2 TMPO
RefSeq:NM_001032284.2 TMPO
Other Identifiers
11731918_a_at
11731919_a_at
11747091_a_at
11747092_x_at
11763585_s_at
11764010_a_at
16755498
209753_PM_s_at
209753_s_at
209754_PM_s_at
209754_s_at
224944_PM_at
224944_at
32682_at
3427776
3427777
3427778
3427779
3427780
3427781
3427788
3427789
3427796
3427797
3427799
3427800
3427802
3427803
3427804
3427805
3427806
3427807
3427808
3427809
3427810
3427811
3427812
3668746
51750_s_at
56493_r_at
7112
7957737
81494_at
A_24_P210244
A_33_P3412613
GE62529
GO:0003677
GO:0005515
GO:0005521
GO:0005634
GO:0005635
GO:0005637
GO:0005737
GO:0016020
GO:0031965
GO:0043226
HMNXSV003003534
Hs.11355.2.S1_3p_a_at
Hs.11355.4.A1_3p_at
ILMN_1677747
ILMN_1795340
PH_hs_0038319
TC12000761.hg
U09087_s_at
U18271_cds3_s_at
g6855608_3p_a_at
Participates
as a candidate of
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
RHOD plasma membrane effectors [cytosol] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
RHOF effectors [cytosol] (Homo sapiens)
RHOG plasma membrane effectors [cytosol] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_001027455.1
,
NP_001294904.1
,
NP_001027454.1
OpenTargets
ENSG00000120802
GeneCards
P42167
Ensembl
ENSP00000450627
,
ENSG00000120802
,
ENST00000393053
,
ENSP00000261210
,
ENST00000556029
,
ENST00000261210
,
ENSP00000376773
PRO
P42167
Pharos - Targets
P42167
Orphanet
17255
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P02545 LMNA
3
LMNA(1-646) [nuclear envelope]
(R-HSA-535479)
LMNA(1-567)-RAF1(279-648) fusion [cytosol]
(R-HSA-6802399)
LMNA(1-567)-p-RAF1(279-648) fusion [cytosol]
(R-HSA-6802537)
0.569
4
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