lorlatinib-resistant ALK mutants [plasma membrane]

Stable Identifier
R-HSA-9714053
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
31943796 Overcoming resistance by ALK compound mutation (I1171S + G1269A) after sequential treatment of multiple ALK inhibitors in non-small cell lung cancer

Takahashi, K, Seto, Y, Okada, K, Uematsu, S, Uchibori, K, Tsukahara, M, Oh-Hara, T, Fujita, N, Yanagitani, N, Nishio, M, Okubo, K, Katayama, R

Thorac Cancer 2020
31616196 TKI-resistant ALK-rearranged lung adenocarcinoma with secondary CTNNB1 p.S45V and tertiary ALK p.I1171N mutations

Ouseph, MM, Taber, A, Khurshid, H, Madison, R, Aswad, BI, Resnick, MB, Yakirevich, E, Ali, SM, Patel, NR

Lung Cancer (Auckl) 2019
29650534 Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer

Yoda, S, Lin, JJ, Lawrence, MS, Burke, BJ, Friboulet, L, Langenbucher, A, Dardaei, L, Prutisto-Chang, K, Dagogo-Jack, I, Timofeevski, S, Hubbeling, H, Gainor, JF, Ferris, LA, Riley, AK, Kattermann, KE, Timonina, D, Heist, RS, Iafrate, AJ, Benes, CH, Lennerz, JK, Mino-Kenudson, M, Engelman, JA, Johnson, TW, Hata, AN, Shaw, AT

Cancer Discov 2018
31749991 Molecular findings reveal possible resistance mechanisms in a patient with ALK-rearranged lung cancer: a case report and literature review

Kougioumtzi, A, Ntellas, P, Papadopoulou, E, Nasioulas, G, Kampletsas, E, Pentheroudakis, G

ESMO Open 2019
Participants
Participates
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
Mondo
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