BIRC6(1-958)-p-7Y-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9713451
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Baculoviral IAP repeat-containing protein 6 ecNumber evidence="9 11"2.3.2.27/ecNumber, BIRC6_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
26001147 BIRC6-ALK, a Novel Fusion Gene in ALK Break-Apart FISH-Negative Lung Adenocarcinoma, Responds to Crizotinib

Ying, J, Zeng, Y, Wu, J, Xu, F, Zhang, W, Jiao, Y, Jiang, P, Guo, L, Shan, L

J Thorac Oncol 2015
External Reference Information
External Reference
UniProt:Q9NR09 BIRC6
Gene Names
BIRC6, KIAA1289
Chain
chain:1-4857
Reference Genes
BioGPS Gene:57448 BIRC6
COSMIC (genes):BIRC6 BIRC6
CTD Gene:57448 BIRC6
dbSNP Gene:57448 BIRC6
ENSEMBL:ENSG00000115760 BIRC6
ENSEMBL_homo_sapiens_GENE:ENSG00000115760.16 BIRC6
HGNC:13516 BIRC6
KEGG Gene (Homo sapiens):57448 BIRC6
Monarch:57448 BIRC6
NCBI Gene:57448 BIRC6
OMIM:605638 BIRC6
UCSC:Q9NR09 BIRC6
Reference Transcript
Other Identifiers
11742930_a_at
11742931_at
16878800
224635_PM_s_at
224635_s_at
233093_PM_s_at
233093_s_at
2476222
2476223
2476224
2476225
2476226
2476227
2476239
2476240
2476243
2476245
2476246
2476250
2476251
2476252
2476253
2476258
2476259
2476260
2476262
2476265
2476267
2476269
2476270
2476271
2476272
2476273
2476274
2476276
2476277
2476279
2476284
2476288
2476289
2476290
2476291
2476292
2476293
2476294
2476295
2476296
2476297
2476298
2476299
2476300
2476301
2476305
2476308
2476311
2476313
2476314
2476315
2476316
2476318
2476322
2476324
2476325
2476326
2476327
2476328
2476329
2476330
2476331
2476332
2476333
2476334
2476335
2476338
2476339
2476340
2476341
2476342
2476344
2476345
2476347
2476348
2476355
2476356
2476359
2476361
2476363
2476364
2476366
2476368
2476379
2476388
2476391
2476392
2476394
2476395
2476399
2476401
2476403
2476404
2476405
2476406
2476407
2476408
2476409
2476410
45215_at
57448
65603_at
8041283
A_14_P122588
A_14_P125649
A_23_P142616
A_33_P3314902
GE62494
GO:0000910
GO:0000922
GO:0001890
GO:0003824
GO:0004842
GO:0004869
GO:0005515
GO:0005634
GO:0005737
GO:0005768
GO:0005794
GO:0005802
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006468
GO:0006915
GO:0007049
GO:0008283
GO:0008284
GO:0012501
GO:0016020
GO:0016567
GO:0016740
GO:0023052
GO:0030414
GO:0030496
GO:0031410
GO:0032465
GO:0036211
GO:0042127
GO:0042981
GO:0043066
GO:0043226
GO:0048856
GO:0051301
GO:0060711
GO:0060712
GO:0061631
GO:0090543
GO:0098772
GO:0140096
GO:2001237
HMNXSV003051151
Hs.250646.0.S2_3p_a_at
Hs.250646.1.S1_3p_a_at
ILMN_1801605
PH_hs_0024017
TC02000213.hg
Participates
as a component of
Other forms of this molecule
BIRC6(1-958)-ALK(1058-1620) fusion [cytosol]
Modified Residues
Name
Insertion of residues 1058 to 1620 at 959 from UniProt:Q9UM73 ALK
Coordinate
959
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1358
Coordinate
1358
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
lung adenocarcinoma DOID:3910 nonsmall cell adenocarcinoma
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
IntEnz
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
HMDB Protein
PDB
Interactors (5)
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