BCL11A(1-219)insDHPPA-p-7Y-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9713447
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
fullName evidence="17"B-cell lymphoma/leukemia 11A, BC11A_HUMAN
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
28404650 Identification of a novel crizotinib-sensitive BCL11A-ALK gene fusion in a nonsmall cell lung cancer patient

Li, ZW, Deng, WJ, Tian, Q

Eur Respir J 2017
External Reference Information
External Reference
UniProt:Q9H165 BCL11A
Gene Names
BCL11A, CTIP1, EVI9, KIAA1809, ZNF856
Chain
chain:1-835
Reference Genes
BioGPS Gene:53335 BCL11A
COSMIC (genes):BCL11A BCL11A
CTD Gene:53335 BCL11A
dbSNP Gene:53335 BCL11A
ENSEMBL:ENSG00000119866 BCL11A
ENSEMBL:ENSG00000119866.22 BCL11A
HGNC:13221 BCL11A
KEGG Gene (Homo sapiens):53335 BCL11A
Monarch:53335 BCL11A
NCBI Gene:53335 BCL11A
OMIM:606557 BCL11A
UCSC:Q9H165 BCL11A
Reference Transcript
Other Identifiers
11723852_a_at
11723853_a_at
11732339_at
11732340_at
11732341_at
11747189_a_at
11749675_a_at
11749676_x_at
16897946
210347_PM_s_at
210347_s_at
219497_PM_s_at
219497_s_at
219498_PM_s_at
219498_s_at
222891_PM_s_at
222891_s_at
2554976
2554977
2554978
2554981
2554982
2554983
2554984
2554985
2554986
2554987
2554988
2554989
2554990
2554991
2554992
2554993
2554994
2554995
2554996
2554999
2555035
2555041
2555042
2555043
2555044
41355_at
42803_at
49862_at
53335
8052399
90185_at
A_23_P218584
A_24_P402588
A_24_P411186
A_33_P3249589
A_33_P3249595
GE63216
GO:0000122
GO:0000978
GO:0001067
GO:0001227
GO:0003677
GO:0003700
GO:0003712
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0010628
GO:0010976
GO:0010977
GO:0016363
GO:0016514
GO:0016925
GO:0019901
GO:0030154
GO:0030517
GO:0032463
GO:0036211
GO:0042382
GO:0042803
GO:0043226
GO:0045944
GO:0046872
GO:0046982
GO:0048671
GO:0048672
GO:0048856
GO:0050773
GO:0065003
GO:0098794
GO:0140110
GO:0140297
GO:1903860
GO:1904800
GO:1905232
GO:2000171
GO:2000173
HMNXSV003037084
HMNXSV003050214
Hs.130881.0.S2_3p_a_at
ILMN_1659800
ILMN_1752899
ILMN_2255133
ILMN_2342271
PH_hs_0023752
TC02001885.hg
g12150277_3p_s_at
g13375629_3p_a_at
g8922264_3p_a_at
p27373
Participates
as a component of
Other forms of this molecule
BCL11A(1-219)insDHPPA-ALK(1058-1620) fusion [cytosol]
Modified Residues
Name
Insertion of residues 1058 to 1620 at 220 from UniProt:Q9UM73 ALK
Coordinate
220
Name
Replacement of residues 219 to 219 by ADHPPA
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1358
Coordinate
1358
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
non-small cell lung carcinoma DOID:3908 Non-small cell lung cancer (disorder), NSCLC, NSCLC
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
PDB
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q09028 RBBP4  1 0.527 2
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