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DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion dimer [cytosol]
Stable Identifier
R-HSA-9712037
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ALK in cancer (Homo sapiens)
Signaling by ALK fusions and activated point mutants (Homo sapiens)
ALK fusions phosphorylate FRS (Homo sapiens)
PI3K-binding ALK mutants [cytosol] (Homo sapiens)
DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
ALK fusions phosphorylate IRS1 (Homo sapiens)
PI3K-binding ALK mutants [cytosol] (Homo sapiens)
DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
ALK mutants bind PI3KCA (Homo sapiens)
ALK mutants:PIK3R1 [cytosol] (Homo sapiens)
PI3K-binding ALK mutants [cytosol] (Homo sapiens)
DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
PI3K-binding ALK fusions:PI3K [cytosol] (Homo sapiens)
ALK mutants:PIK3R1 [cytosol] (Homo sapiens)
PI3K-binding ALK mutants [cytosol] (Homo sapiens)
DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
ALK mutants bind PI3KR1 (Homo sapiens)
ALK mutants:PIK3R1 [cytosol] (Homo sapiens)
PI3K-binding ALK mutants [cytosol] (Homo sapiens)
DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
PI3K-binding ALK mutants [cytosol] (Homo sapiens)
DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
Autophosphorylation of ALK fusions (Homo sapiens)
p-7Y ALK fusion protein dimers [cytosol] (Homo sapiens)
DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
PI3K synthesizes PIP3 downstream of ALK mutants (Homo sapiens)
PI3K-binding ALK fusions:PI3K [cytosol] (Homo sapiens)
ALK mutants:PIK3R1 [cytosol] (Homo sapiens)
PI3K-binding ALK mutants [cytosol] (Homo sapiens)
DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
PI3K-binding ALK mutants [cytosol] (Homo sapiens)
DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
Participants
components
x 2
DCTN1(1-1177)-p-7Y-ALK(1058-1620) fusion [cytosol]
(Homo sapiens)
Participates
as a candidate of
p-7Y ALK fusion protein dimers [cytosol] (Homo sapiens)
PI3K-binding ALK mutants [cytosol] (Homo sapiens)
Disease
Name
Identifier
Synonyms
inflammatory myofibroblastic tumor
DOID:0050905
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