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IRS:ALK fusion proteins [cytosol]
Stable Identifier
R-HSA-9711940
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ALK in cancer (Homo sapiens)
Signaling by ALK fusions and activated point mutants (Homo sapiens)
ALK fusion proteins bind IRS (Homo sapiens)
IRS:ALK fusion proteins [cytosol] (Homo sapiens)
ALK fusions phosphorylate IRS1 (Homo sapiens)
IRS:ALK fusion proteins [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
8633037
Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)
Yamamoto, T
,
Iwahara, T
,
Satoh, H
,
Seki, N
,
Fujimoto, J
,
Mori, S
,
Shiota, M
Proc. Natl. Acad. Sci. U.S.A.
1996
Participants
components
IRS- and FRS-binding ALK fusion proteins [cytosol]
(Homo sapiens)
IRS1 [cytosol]
(Homo sapiens)
Participates
as an output of
ALK fusion proteins bind IRS (Homo sapiens)
as an input of
ALK fusions phosphorylate IRS1 (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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