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GSDME oligomer:PIP [plasma membrane]
Stable Identifier
R-HSA-9710248
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Regulation of TLR by endogenous ligand (Homo sapiens)
HMGB1 release from cells (Homo sapiens)
GSDME oligomer:PIP [plasma membrane] (Homo sapiens)
Programmed Cell Death (Homo sapiens)
Regulated Necrosis (Homo sapiens)
Pyroptosis (Homo sapiens)
GSDME oligomerizes (Homo sapiens)
GSDME oligomer:PIP [plasma membrane] (Homo sapiens)
HMGB1 release from cells (Homo sapiens)
GSDME oligomer:PIP [plasma membrane] (Homo sapiens)
Participants
components
x 3
GSDME(1-270) [cytosol]
(Homo sapiens)
x 2
PI4P,PI(4,5)P2,PIP3 [plasma membrane]
Participates
as an output of
GSDME oligomerizes (Homo sapiens)
This entity regulates
Positively
HMGB1 release from cells
(Homo sapiens)
Inferred To
GSDME oligomer:PIP [plasma membrane]
(Bos taurus)
GSDME oligomer:PIP [plasma membrane]
(Canis familiaris)
GSDME oligomer:PIP [plasma membrane]
(Danio rerio)
GSDME oligomer:PIP [plasma membrane]
(Gallus gallus)
GSDME oligomer:PIP [plasma membrane]
(Mus musculus)
GSDME oligomer:PIP [plasma membrane]
(Rattus norvegicus)
GSDME oligomer:PIP [plasma membrane]
(Sus scrofa)
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