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MAVS:TOMM70 [mitochondrial outer membrane]
Stable Identifier
R-HSA-9709860
Type
Complex
Species
Homo sapiens
Compartment
mitochondrial outer membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
SARS-CoV-1-host interactions (Homo sapiens)
SARS-CoV-1 activates/modulates innate immune responses (Homo sapiens)
SARS-CoV-1 3a binds TRAF3 within NLRP3 inflammasome (Homo sapiens)
3a:NLRP3 oligomer:MAVS:TRAF3:PYCARD [mitochondrial outer membrane] (Homo sapiens)
NLRP3 oligomer:MAVS:TRAF3:PYCARD [mitochondrial outer membrane] (Homo sapiens)
NLRP3 oligomer:MAVS:TRAF3 [mitochondrial outer membrane] (Homo sapiens)
NLRP3:MAVS:TOMM70 [mitochondrial outer membrane] (Homo sapiens)
MAVS:TOMM70 [mitochondrial outer membrane] (Homo sapiens)
NLRP3 oligomer:MAVS:TRAF3:PYCARD [mitochondrial outer membrane] (Homo sapiens)
NLRP3 oligomer:MAVS:TRAF3 [mitochondrial outer membrane] (Homo sapiens)
NLRP3:MAVS:TOMM70 [mitochondrial outer membrane] (Homo sapiens)
MAVS:TOMM70 [mitochondrial outer membrane] (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
MAVS:TOMM70 recruits HSP90:TBK1:IRF3 (Homo sapiens)
MAVS:TOMM70 [mitochondrial outer membrane] (Homo sapiens)
MAVS:TOMM70:HSP90:TBK1:IRF3 [mitochondrial outer membrane] (Homo sapiens)
MAVS:TOMM70 [mitochondrial outer membrane] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
MAVS binds TOMM70 (Homo sapiens)
MAVS:TOMM70 [mitochondrial outer membrane] (Homo sapiens)
MAVS:TOMM70 recruits HSP90:TBK1:IRF3 (Homo sapiens)
MAVS:TOMM70 [mitochondrial outer membrane] (Homo sapiens)
MAVS:TOMM70:HSP90:TBK1:IRF3 [mitochondrial outer membrane] (Homo sapiens)
MAVS:TOMM70 [mitochondrial outer membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
20628368
Tom70 mediates activation of interferon regulatory factor 3 on mitochondria
Wang, C
,
Shi, HX
,
Liu, XY
,
Shan, YF
,
Wei, B
Cell Res
2010
Participants
components
MAVS [mitochondrial outer membrane]
(Homo sapiens)
TOMM70 [mitochondrial outer membrane]
(Homo sapiens)
Participates
as a component of
NLRP3:MAVS:TOMM70 [mitochondrial outer membrane] (Homo sapiens)
MAVS:TOMM70:HSP90:TBK1:IRF3 [mitochondrial outer membrane] (Homo sapiens)
as an output of
MAVS binds TOMM70 (Homo sapiens)
as an input of
MAVS:TOMM70 recruits HSP90:TBK1:IRF3 (Homo sapiens)
Inferred To
MAVS:TOMM70 [mitochondrial outer membrane]
(Bos taurus)
MAVS:TOMM70 [mitochondrial outer membrane]
(Canis familiaris)
MAVS:TOMM70 [mitochondrial outer membrane]
(Danio rerio)
MAVS:TOMM70 [mitochondrial outer membrane]
(Gallus gallus)
MAVS:TOMM70 [mitochondrial outer membrane]
(Mus musculus)
MAVS:TOMM70 [mitochondrial outer membrane]
(Rattus norvegicus)
MAVS:TOMM70 [mitochondrial outer membrane]
(Sus scrofa)
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