CO translocates from cytosol to mitochondrial inner membrane

Stable Identifier
R-HSA-9709366
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
cytosol, mitochondrial inner membrane
Synonyms
CO diffuses into the mitochondrial inner membrane
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CO translocates from cytosol to mitochondrial inner membrane
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As a light, unpolar molecule carbon monoxide (CO) is able to penetrate lipid membranes and so get access to proteins in the inner mitochondrial membrane (Alonso et al, 2003).

Literature References
PubMed ID Title Journal Year
12969439 Carbon monoxide specifically inhibits cytochrome c oxidase of human mitochondrial respiratory chain

Miró, O, López, S, Casademont, J, Alonso, JR, Cardellach, F

Pharmacol Toxicol 2003
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Authored
Stephan, R  (2020-12-03)
Reviewed
Somers, J  (2021-01-23)
Created
Stephan, R  (2020-12-14)
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