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CO translocates from cytosol to mitochondrial inner membrane
Stable Identifier
R-HSA-9709366
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
,
mitochondrial inner membrane
Synonyms
CO diffuses into the mitochondrial inner membrane
ReviewStatus
5/5
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Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
CO translocates from cytosol to mitochondrial inner membrane (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
As a light, unpolar molecule carbon monoxide (CO) is able to penetrate lipid membranes and so get access to proteins in the inner mitochondrial membrane (Alonso et al, 2003).
Literature References
PubMed ID
Title
Journal
Year
12969439
Carbon monoxide specifically inhibits cytochrome c oxidase of human mitochondrial respiratory chain
Miró, O
,
López, S
,
Casademont, J
,
Alonso, JR
,
Cardellach, F
Pharmacol Toxicol
2003
Participants
Input
CO [cytosol]
Output
CO [mitochondrial inner membrane]
Participates
as an event of
Cytoprotection by HMOX1 (Homo sapiens)
Authored
Stephan, R (2020-12-03)
Reviewed
Somers, J (2021-01-23)
Created
Stephan, R (2020-12-14)
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