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HM13 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-9708544
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
SPP
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
Regulation of HMOX1 expression and activity (Homo sapiens)
HM13 cleaves HMOX1 dimer (Homo sapiens)
HM13 [endoplasmic reticulum membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
15998642
Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3
Steiner, H
,
Fluhrer, R
,
Haass, C
,
Haffner, C
,
Krawitz, P
,
Schmid, B
J Biol Chem
2005
External Reference Information
External Reference
UniProt:Q8TCT9 HM13
Gene Names
HM13, H13, IMP1, PSL3, SPP, MSTP086
Chain
chain:1-377
Reference Genes
BioGPS Gene:81502 HM13
COSMIC (genes):HM13 HM13
CTD Gene:81502 HM13
dbSNP Gene:81502 HM13
ENSEMBL:ENSG00000101294 HM13
HGNC:16435 HM13
Monarch:81502 HM13
NCBI Gene:81502 HM13
OMIM:607106 HM13
UCSC:Q8TCT9 HM13
Reference Transcript
RefSeq:NM_030789.3 HM13
RefSeq:NM_178581.2 HM13
RefSeq:NM_178580.2 HM13
RefSeq:NM_178582.2 HM13
Other Identifiers
11716646_a_at
11716647_x_at
11723016_a_at
11723017_x_at
11736301_at
11740470_x_at
1557148_PM_at
1557148_at
1558561_3p_at
1558561_PM_at
1558561_at
16912358
224615_PM_x_at
224615_x_at
230107_PM_at
230107_at
232209_PM_x_at
232209_x_at
3881288
3881289
3881290
3881291
3881295
3881296
3881299
3881300
3881301
3881302
3881303
3881304
3881305
3881306
3881307
3881308
3881320
3881321
3881322
3881323
3881324
3881326
3881327
3881328
3881329
3881330
3881332
3881333
3881334
3881335
3881336
3881337
3881338
3881339
3881340
3881341
3881342
3881343
3881344
3881345
3881346
3881347
3881348
3881349
3881350
3881351
3881352
3881353
3881354
3881355
3881356
3881357
3881358
3881363
49181_at
55366_at
79029_at
8061542
81502
A_14_P137563
A_23_P396867
A_23_P40347
A_33_P3323448
A_33_P3323453
GE541217
GE80775
GO:0001701
GO:0003824
GO:0005515
GO:0005783
GO:0005789
GO:0005791
GO:0005886
GO:0006465
GO:0006508
GO:0008233
GO:0009986
GO:0016020
GO:0016787
GO:0031625
GO:0033619
GO:0034599
GO:0036513
GO:0042500
GO:0042803
GO:0043226
GO:0048856
GO:0051604
GO:0098553
GO:0098554
GO:0140096
GO:1904211
HMNXSV003023300
HMNXSV003035869
HMNXSV003045343
Hs.306163.1.A1_3p_a_at
Hs.306163.2.A1_3p_x_at
Hs.87680.0.A1_3p_at
Hs2.399742.1.S1_3p_at
Hs2.399742.1.S1_3p_x_at
Hs2.400006.1.S1_3p_at
ILMN_1687833
ILMN_1766269
ILMN_1807833
ILMN_2236655
PH_hs_0025979
TC20001185.hg
p10558
Inferred To
Hm13 [endoplasmic reticulum membrane]
(Mus musculus)
Hm13 [endoplasmic reticulum membrane]
(Rattus norvegicus)
Spp [endoplasmic reticulum membrane]
(Drosophila melanogaster)
HM13 [endoplasmic reticulum membrane]
(Bos taurus)
HM13 [endoplasmic reticulum membrane]
(Canis familiaris)
HM13 [endoplasmic reticulum membrane]
(Sus scrofa)
A0A1D5PUL3 [endoplasmic reticulum membrane]
(Gallus gallus)
Cross References
ENSEMBL
ENSP00000381237
,
ENST00000398174
,
ENST00000340852
,
ENSP00000501423
,
ENST00000674240
,
ENSP00000343032
OpenTargets
ENSG00000101294
HPA
ENSG00000101294-HM13
PRO
Q8TCT9
Pharos - Targets
Q8TCT9
GlyGen
Q8TCT9
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BRK4 LZTS2
0.556
3
UniProt:Q8WU17 RNF139
1
RNF139 [endoplasmic reticulum membrane]
(R-HSA-8861805)
0.524
2
UniProt:P17861-1 XBP1
0.524
2
UniProt:Q9BUN8 DERL1
1
DERL1 [endoplasmic reticulum membrane]
(R-HSA-6781898)
0.524
6
UniProt:P27105 STOM
4
STOM [azurophil granule membrane]
(R-HSA-6800997)
STOM [plasma membrane]
(R-HSA-6806258)
STOM [specific granule membrane]
(R-HSA-6799569)
STOM [tertiary granule membrane]
(R-HSA-6800960)
0.508
2
UniProt:A0A0F6B5H5 A0A0F6B5H5
0.462
2
UniProt:A0A0F6B1Q8 A0A0F6B1Q8
0.462
2
UniProt:P04578 env
7
ENV [viral envelope]
(R-HIV-173439)
Surface protein gp120 [viral envelope]
(R-HIV-171211)
Transmembrane protein gp41 [viral envelope]
(R-HIV-171195)
Envelope glycoprotein gp160 [endoplasmic reticulum membrane]
(R-HIV-189343)
Glycosylated Envelope glycoprotein gp160 [Golgi membrane]
(R-HIV-3149443)
Transmembrane protein gp41 (P04578) [cytosol]
(R-HIV-189359)
Surface protein gp120 (P04578) [cytosol]
(R-HIV-189269)
0.462
2
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