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CSF3 [lysosomal lumen]
Stable Identifier
R-HSA-9707917
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
G-CSF, Granulocyte colony-stimulating factor
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by CSF3 (G-CSF) (Homo sapiens)
Inactivation of CSF3 (G-CSF) signaling (Homo sapiens)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Homo sapiens)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [lysosomal membrane] (Homo sapiens)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1 [lysosomal membrane] (Homo sapiens)
CSF3 dimer:K48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1 [lysosomal membrane] (Homo sapiens)
CSF3 dimer [lysosomal lumen] (Homo sapiens)
CSF3 [lysosomal lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P09919 CSF3
Gene Names
CSF3, C17orf33, GCSF
Chain
signal peptide:1-30, chain:31-207
Reference Genes
BioGPS Gene:1440 CSF3
COSMIC (genes):CSF3 CSF3
CTD Gene:1440 CSF3
dbSNP Gene:1440 CSF3
ENSEMBL:ENSG00000108342 CSF3
ENSEMBL_homo_sapiens_GENE:ENSG00000108342.13 CSF3
HGNC:2438 CSF3
KEGG Gene (Homo sapiens):1440 CSF3
Monarch:1440 CSF3
NCBI Gene:1440 CSF3
OMIM:138970 CSF3
UCSC:P09919 CSF3
Reference Transcript
RefSeq:NM_172220.2 CSF3
RefSeq:NM_001178147.1 CSF3
RefSeq:NM_172219.2 CSF3
RefSeq:NM_000759.3 CSF3
Other Identifiers
11729512_a_at
11729513_x_at
11729514_a_at
1334_s_at
1440
16833953
207442_PM_at
207442_at
3720677
3720680
3720684
3720686
3720687
3720688
3720689
3720690
8006999
A_14_P128877
A_23_P501754
A_33_P3222424
GE59652
GO:0002376
GO:0005125
GO:0005130
GO:0005576
GO:0005615
GO:0005764
GO:0005773
GO:0006351
GO:0006355
GO:0006955
GO:0007010
GO:0007165
GO:0008083
GO:0008284
GO:0019221
GO:0019899
GO:0023052
GO:0030154
GO:0030838
GO:0030851
GO:0031410
GO:0036211
GO:0038158
GO:0043202
GO:0043226
GO:0045471
GO:0045639
GO:0045944
GO:0048018
GO:0048856
GO:0050731
GO:0051897
GO:0065003
GO:0071222
GO:0071345
GO:0071682
GO:0098772
GO:0110053
HMNXSV003025460
ILMN_1697069
ILMN_2322768
PH_hs_0000295
TC17000486.hg
TC17002194.hg
X03656_rna1_at
g4503078_3p_at
Participates
as a component of
CSF3 dimer [lysosomal lumen] (Homo sapiens)
Other forms of this molecule
CSF3 [endocytic vesicle lumen]
CSF3 [extracellular region]
Inferred To
CSF3 [lysosomal lumen]
(Bos taurus)
CSF3 [lysosomal lumen]
(Canis familiaris)
CSF3 [lysosomal lumen]
(Gallus gallus)
CSF3 [lysosomal lumen]
(Sus scrofa)
Ghost homologue of CSF3 [lysosomal lumen]
(Drosophila melanogaster)
Homologues of CSF3 [lysosomal lumen]
(Sus scrofa)
Csf3 [lysosomal lumen]
(Mus musculus)
Csf3 [lysosomal lumen]
(Rattus norvegicus)
csf3 [lysosomal lumen]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000750.1
,
NP_757374.2
,
NP_757373.1
,
NP_001171618.1
OpenTargets
ENSG00000108342
HPA
ENSG00000108342-CSF3
GeneCards
P09919
Ensembl
ENST00000225474
,
ENSP00000377705
,
ENST00000394148
,
ENST00000394149
,
ENSP00000377704
,
ENSG00000108342
,
ENSP00000225474
PRO
P09919
Pharos - Targets
P09919
PDB
1GNC
,
5GW9
,
1CD9
,
1PGR
,
1RHG
,
5ZO6
,
2D9Q
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