Active FLT3 binds to SYK

Stable Identifier
R-HSA-9706336
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Spleen-associated tyrosine kinase (SYK) binds to active FLT3 and transactivates it (Puissant et al, 2014).

Literature References
PubMed ID Title Journal Year
24525236 SYK is a critical regulator of FLT3 in acute myeloid leukemia

Puissant, A, Fenouille, N, Alexe, G, Pikman, Y, Bassil, CF, Mehta, S, Du, J, Kazi, JU, Luciano, F, Rönnstrand, L, Kung, AL, Aster, JC, Galinsky, I, Stone, RM, Deangelo, DJ, Hemann, MT, Stegmaier, K

Cancer Cell 2014
Participants
Participant Of
Orthologous Events
Authored
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Created
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