ETV6(1-154insGSFILG)-FLT3(573-993) fusion [cytosol]

Stable Identifier
R-HSA-9703312
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Transcription factor ETV6, ETV6_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
21705501 Response of ETV6-FLT3-positive myeloid/lymphoid neoplasm with eosinophilia to inhibitors of FMS-like tyrosine kinase 3

Score, J, Erben, P, Haferlach, C, Gesk, S, Ritter, M, Telford, N, Haferlach, T, Reiter, A, Cross, NC, Metzgeroth, G, Hofmann, WK, Walz, C, Bloor, A, Hochhaus, A

2011
External Reference Information
External Reference
UniProt:P41212 ETV6
Gene Names
ETV6, TEL, TEL1
Chain
chain:1-452
Reference Genes
BioGPS Gene:2120 ETV6
COSMIC (genes):ETV6 ETV6
CTD Gene:2120 ETV6
dbSNP Gene:2120 ETV6
ENSEMBL:ENSG00000139083 ETV6
HGNC:3495 ETV6
KEGG Gene (Homo sapiens):2120 ETV6
Monarch:2120 ETV6
NCBI Gene:2120 ETV6
OMIM:600618 ETV6
UCSC:P41212 ETV6
Reference Transcript
Other Identifiers
0004050433
11743165_at
11743166_at
11743167_at
1638_at
16748407
205585_at
2120
225764_at
235056_at
3405041
3405042
3405100
3405132
3405142
3405152
3405156
3405157
3405162
3405163
3405164
3405175
3405177
38491_at
55594_at
58239_at
7953981
A_14_P113857
A_23_P105264
A_24_P372862
A_33_P3210343
A_33_P3356325
GE79814
GO:0000003
GO:0000122
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0001227
GO:0001228
GO:0002376
GO:0003674
GO:0003677
GO:0003700
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005694
GO:0005730
GO:0005737
GO:0005829
GO:0005886
GO:0006355
GO:0006357
GO:0007296
GO:0008150
GO:0008219
GO:0008283
GO:0009058
GO:0019904
GO:0022008
GO:0030154
GO:0034641
GO:0043226
GO:0043565
GO:0045944
GO:0048856
GO:0071425
GO:0097152
HMNXSV003053967
Hs.146381.2.S1_3p_at
Hs.293972.0.S1_3p_at
ILMN_1789596
PH_hs_0034188
TC12003210.hg
U11732_at
g4503610_3p_at
Participates
as a component of
Other forms of this molecule
p-12Y ETV6(1-154)-PDGFRB(527-1106) fusion [plasma membrane]
p-11Y ETV6(1-384)-PDGFRA(552-1089) fusion [plasma membrane]
ETV6(1-154)-PDGFRB(527-1106) fusion [plasma membrane]
ETV6(1-384)-PDGFRA(552-1089) fusion [plasma membrane]
ETV6(1-384)-p-6Y FLT3(573-993) fusion [cytosol]
ETV6(1-154insGSFILG)-p-6Y FLT3(573-993) fusion [cytosol]
ETV6(1-338insGCS)-p-6Y FLT3(573-993) fusion [cytosol]
ETV6(1-301)-p-6Y FLT3(574-993) fusion [cytosol]
ETV6(1-384)-p-3Y FLT3(659-1620) fusion [cytosol]
ETV6(1-338insGCS)-FLT3(573-993) fusion [cytosol]
ETV6(1-384)-FLT3(573-993) fusion [cytosol]
ETV6(1-301)-FLT3(574-993) fusion [cytosol]
ETV6(1-384)-FLT3(569-993) fusion [cytosol]
Modified Residues
Name
Insertion of residues 573 to 993 at 155 from UniProt:P36888 FLT3
Coordinate
155
Name
Replacement of residues 154 to 154 by EGSFILG
Disease
Name Identifier Synonyms
myeloproliferative neoplasm DOID:2226 CMPD, chronic myeloproliferative disease, CMPD, U
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
PRO
PDB
GeneCards
HPA
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
Interactors (2)
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