TRIP11(2-1724)-p-4Y FLT3(594-993) fusion [cytosol]

Stable Identifier
R-HSA-9703304
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Thyroid receptor-interacting protein 11, TRIPB_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
29025582 A novel TRIP11-FLT3 fusion in a patient with a myeloid/lymphoid neoplasm with eosinophilia

Fisk, DG, Fire, AZ, Gojenola, L, Li, X, Arber, DA, Gotlib, J, Roskin, KM, Von Gehr, A, Hou, Y, Zehnder, JL, Bangs, CD, Cherry, AM, Ohgami, RS, Merker, JD, Chung, A

2017
External Reference Information
External Reference
UniProt:Q15643 TRIP11
Gene Names
TRIP11, CEV14
Chain
initiator methionine:1, chain:2-1979
Reference Genes
BioGPS Gene:9321 TRIP11
COSMIC (genes):TRIP11 TRIP11
CTD Gene:9321 TRIP11
dbSNP Gene:9321 TRIP11
ENSEMBL:ENSG00000100815.12 TRIP11
HGNC:12305 TRIP11
KEGG Gene (Homo sapiens):9321 TRIP11
Monarch:9321 TRIP11
NCBI Gene:9321 TRIP11
OMIM:604505 TRIP11
UCSC:Q15643 TRIP11
Reference Transcript
Other Identifiers
0002370369
11742759_a_at
16795987
209778_PM_at
209778_at
230211_PM_at
230211_at
236160_PM_at
236160_at
3576811
3576813
3576814
3576815
3576816
3576817
3576818
3576819
3576820
3576822
3576823
3576824
3576834
3576836
3576838
3576840
3576841
3576842
3576843
3576844
3576845
3576846
3576847
3576850
3576851
3576852
3576853
3576854
3576855
3576862
3576866
3576867
37932_at
55474_at
7980923
81684_at
82204_at
9321
A_23_P106241
A_24_P282172
GE60298
GO:0000139
GO:0002079
GO:0002080
GO:0002081
GO:0003281
GO:0003413
GO:0003713
GO:0005515
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005793
GO:0005794
GO:0005801
GO:0005856
GO:0006351
GO:0006355
GO:0006366
GO:0006486
GO:0006888
GO:0007030
GO:0016020
GO:0016192
GO:0016607
GO:0030133
GO:0030154
GO:0031267
GO:0031410
GO:0033116
GO:0036211
GO:0043226
GO:0045893
GO:0048856
GO:0051216
GO:0060122
GO:0060348
GO:0090161
GO:0099041
GO:1901135
HMNXSV003031390
HMNXSV003047524
Hs.122826.0.A1_3p_at
Hs.95097.0.A1_3p_at
ILMN_1658144
ILMN_1897810
L40380_at
PH_hs_0022719
TC14001444.hg
g2253416_3p_at
Participates
as a component of
Other forms of this molecule
TRIP11 [transport vesicle]
TRIP11 [Golgi membrane]
TRIP11(2-1724)-FLT3(594-993) fusion [cytosol]
Modified Residues
Name
Insertion of residues 594 to 1620 at 1725 from UniProt:P36888 FLT3
Coordinate
1725
Name
O4'-phospho-L-tyrosine at 599
Coordinate
599
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 768
Coordinate
768
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 955
Coordinate
955
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 969
Coordinate
969
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Orphanet
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q04917 YWHAH  1 0.527 2
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