TTT-3002-sensitive FLT3 mutants [plasma membrane]

Stable Identifier
R-HSA-9702992
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
24408321 TTT-3002 is a novel FLT3 tyrosine kinase inhibitor with activity against FLT3-associated leukemias in vitro and in vivo

Levis, M, Duffield, A, Nguyen, B, Small, D, Zhao, M, Williams, A, Greenblatt, S, Li, L, Rudek, M, Ma, H

Blood 2014
28077790 FLT3 activating mutations display differential sensitivity to multiple tyrosine kinase inhibitors

Levis, M, Nguyen, B, Williams, AB, Small, D, Brown, P, Li, L, Young, DJ, Ma, H

Oncotarget 2017
25060518 FLT3 kinase inhibitor TTT-3002 overcomes both activating and drug resistance mutations in FLT3 in acute myeloid leukemia

Ma, HS, Nguyen, B, Williams, AB, Levis, MJ, Small, D, Duffield, AS, Leahy, DJ, Brown, PA, Galanis, A, Li, L

Cancer Res. 2014
Participants
Participates
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
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