IL2RG gene expression downstream of ALK signaling

Stable Identifier
R-HSA-9701556
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
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IL2RG gene expression is repressed by a complex of SIN3A and acetylated, phosphorylated STAT3 dimer downstream of ALK signaling (Gambi et al, 2019).

Literature References
PubMed ID Title Journal Year
30692217 The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3

Verma, A, Inghirami, G, Gambi, G, Wang, R, Elemento, O, Basso, V, Di Simone, E, Mondino, A, Ponzoni, M, Icardi, L, Ricci, L

Cancer Res. 2019
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