Reactome | ALK dimer:ligand:type I ALK binding TKI [plasma membrane]

ALK dimer:ligand:type I ALK binding TKI [plasma membrane]

Stable Identifier

R-HSA-9700592

Type

Complex

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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Participants

components

Participates

as an output of

Liganded-ALK dimer binds type I ALK-binding TKIs (Homo sapiens)

This entity regulates

Negatively

ALK autophosphorylation (Homo sapiens)

Inferred To

ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Bos taurus)

ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Canis familiaris)

ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Danio rerio)

ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Gallus gallus)

ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Mus musculus)

ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Rattus norvegicus)

ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Sus scrofa)

Disease

Name	Identifier	Synonyms
cancer	DOID:162	malignant tumor, malignant neoplasm, primary cancer

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