brigatinib-sensitive ALK mutants [plasma membrane]

Stable Identifier
R-HSA-9700552
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
25228534 Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib

Katayama, R, Friboulet, L, Koike, S, Lockerman, EL, Khan, TM, Gainor, JF, Iafrate, AJ, Takeuchi, K, Taiji, M, Okuno, Y, Fujita, N, Engelman, JA, Shaw, AT

Clin Cancer Res 2014
23239810 Crizotinib-resistant NPM-ALK mutants confer differential sensitivity to unrelated Alk inhibitors

Ceccon, M, Mologni, L, Bisson, W, Scapozza, L, Gambacorti-Passerini, C

Mol. Cancer Res. 2013
25421750 Treatment Efficacy and Resistance Mechanisms Using the Second-Generation ALK Inhibitor AP26113 in Human NPM-ALK-Positive Anaplastic Large Cell Lymphoma

Ceccon, M, Mologni, L, Giudici, G, Piazza, R, Pirola, A, Fontana, D, Gambacorti-Passerini, C

Mol. Cancer Res. 2015
Participants
members
Participates
as a member of
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
Mondo
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