Active ALK phosphorylates FRS2

Stable Identifier
R-HSA-9700164
Type
Reaction
Species
Homo sapiens
Compartment
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FRS2 is phosphorylated downstream of ALK in a manner that depends on ALK kinase activity (Degoutin et al, 2007).

Literature References
PubMed ID Title Journal Year
17274988 ALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiation

Vigny, M, Degoutin, J, Gouzi, JY

FEBS Lett. 2007
Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of Active ALK:FRS2 [plasma membrane]

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