semaxanib-sensitive FLT3 mutants [plasma membrane]

Stable Identifier
R-HSA-9699545
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
15626738 FLT3-ITD-TKD dual mutants associated with AML confer resistance to FLT3 PTK inhibitors and cytotoxic agents by overexpression of Bcl-x(L)

Bagrintseva, K, Geisenhof, S, Kern, R, Eichenlaub, S, Reindl, C, Ellwart, JW, Hiddemann, W, Spiekermann, K

Blood 2005
12406902 The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3

Spiekermann, K, Dirschinger, RJ, Schwab, R, Bagrintseva, K, Faber, F, Buske, C, Schnittger, S, Kelly, LM, Gilliland, DG, Hiddemann, W

Blood 2003
12351406 SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase

Yee, KW, O'Farrell, AM, Smolich, BD, Cherrington, JM, McMahon, G, Wait, CL, McGreevey, LS, Griffith, DJ, Heinrich, MC

Blood 2002
Participants
Participant Of
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Cite Us!