semaxanib-sensitive FLT3 mutants [plasma membrane]

Stable Identifier
R-HSA-9699545
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
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Literature References
PubMed ID Title Journal Year
15626738 FLT3-ITD-TKD dual mutants associated with AML confer resistance to FLT3 PTK inhibitors and cytotoxic agents by overexpression of Bcl-x(L)

Bagrintseva, K, Geisenhof, S, Kern, R, Eichenlaub, S, Reindl, C, Ellwart, JW, Hiddemann, W, Spiekermann, K

Blood 2005
12406902 The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3

Spiekermann, K, Dirschinger, RJ, Schwab, R, Bagrintseva, K, Faber, F, Buske, C, Schnittger, S, Kelly, LM, Gilliland, DG, Hiddemann, W

Blood 2003
12351406 SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase

Yee, KW, O'Farrell, AM, Smolich, BD, Cherrington, JM, McMahon, G, Wait, CL, McGreevey, LS, Griffith, DJ, Heinrich, MC

Blood 2002
Participants
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Participant Of
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Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
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